Dyab, A., Monib, M., Amin, M., Hawary, B., Desoky, R. (2018). Cryptosporidiosis in Immunocompromised Children. test, 27(2), 143-149. doi: 10.21608/ejmm.2018.285568
Ahmed K. Dyab; Mohammed El-salahy M. Monib; Mohamed M. Amin; Bahaa Hawary; Rehab M. Desoky. "Cryptosporidiosis in Immunocompromised Children". test, 27, 2, 2018, 143-149. doi: 10.21608/ejmm.2018.285568
Dyab, A., Monib, M., Amin, M., Hawary, B., Desoky, R. (2018). 'Cryptosporidiosis in Immunocompromised Children', test, 27(2), pp. 143-149. doi: 10.21608/ejmm.2018.285568
Dyab, A., Monib, M., Amin, M., Hawary, B., Desoky, R. Cryptosporidiosis in Immunocompromised Children. test, 2018; 27(2): 143-149. doi: 10.21608/ejmm.2018.285568

Cryptosporidiosis in Immunocompromised Children

Egyptian Journal of Medical Microbiology
Volume 27, Issue 2, April 2018, Pages 143-149    PDF (392.67 K)
Document Type: New and original researches in the field of Microbiology.
DOI: 10.21608/ejmm.2018.285568
Authors
Ahmed K. Dyab1; Mohammed El-salahy M. Monib1; Mohamed M. Amin* 2; Bahaa Hawary3; Rehab M. Desoky4
1Department of Medical Parasitology Faculty of Medicine, Assiut University
2Department of Microbiology and immunology, Faculty of Medicine, Aswan University
3Department of pediatrics, Faculty of Medicine, Aswan University
4Department of Medical Parasitology Faculty of Medicine, Aswan University
Abstract
Background: Cryptosporidium parvum is an obligate intracellular parasite of the Coccidia class that infects the microvilli epithelial cells of the digestive and respiratory systems Objectives: this study aims to detection of the prevalence of cryptosporidiosis among immune compromised children who receive chemotherapy and to compare the three different methods for diagnosis of Cryptosporidium Methodology: 200 children in Aswan oncology institute were enrolled in this study, clinical assessment as well as stool examination by modified Ziehl-Neelsen stain, ELISA assay and Immunofluorescence tests were done. Results: The study showed that the over-all infection was 43.5% by immunofluorescence method, 40.5% by ELISA and 28% by modified Ziehl-Neelsen stain. Infection rate increases in haematological malignancies (AML54.8%, HD46.2 %, ALL41.6%, NON HD 27.3%) than non haematological malignancy (wilms 50%, sarcoma 45.5%, and neuroblastoma 42.9%). Conclusion: Cryptosporidium infection is an important public health problem in Immunocompromised children, raising awareness about cryptosporidiosis has very important effect to decrease prevalence of this parasitic infection.
Keywords
Cryptosporidium; AML (acute myeloid leukemia); HD (Hodgkin lymphoma); Non HD (Non-Hodgkin lymphoma) and ALL (acute lymphoblastic leukemia)
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