Eid, M., Magdy, M., El-Sawaf, A., El-Demiry, N. (2023). Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage. test, 27(1), 27-34. doi: 10.21608/egyfs.2023.286056
Marwa Mohamed Eid; Marwa Magdy; Ahmed El-Sawaf; Nihal M. El-Demiry. "Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage". test, 27, 1, 2023, 27-34. doi: 10.21608/egyfs.2023.286056
Eid, M., Magdy, M., El-Sawaf, A., El-Demiry, N. (2023). 'Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage', test, 27(1), pp. 27-34. doi: 10.21608/egyfs.2023.286056
Eid, M., Magdy, M., El-Sawaf, A., El-Demiry, N. Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage. test, 2023; 27(1): 27-34. doi: 10.21608/egyfs.2023.286056

Role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage

The Egyptian Journal of Fertility and Sterility
Volume 27, Issue 1 - Serial Number 11106352, January 2023, Pages 27-34    PDF (2.95 M)
Document Type: Original Article
DOI: 10.21608/egyfs.2023.286056
Authors
Marwa Mohamed Eid* 1; Marwa Magdy2; Ahmed El-Sawaf3; Nihal M. El-Demiry4
1Assistant Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.
2Obstetrics and Gynecology resident, Bolak Eldakror hospital, Department of Obstetrics and Gynecology, Bolak Eldakror hospital, MOH, Cairo, Egypt.
3Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.
4Lecturer of Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Faculty of Medicine-Cairo University, Cairo, Egypt.
Abstract
Background: Prophylactic antibiotics have been tradi- tionally used to prevent postoperative infection after sur- gical intervention for the first-trimester miscarriage. This work aims to study the role of prophylactic antibiotics in preventing pelvic infection after surgical management of first-trimester miscarriage.
Methods: This study was conducted on 138 women who underwent surgical management of first-trimester mis- carriage. They were equally divided into two groups; the women in the study group were given a single dose of oral doxycycline (200 mg) and metronidazole (500 mg) 2 hours before the surgical procedure. The other group was given a placebo. Both groups were followed up for assessment of postoperative infection within two weeks.  
Results: According to the original strict criteria, the preva- lence of pelvic infection was found in 8.7% in the antibiotic group (6 out of 69) and 13% in the placebo group (9 out of 69), P=0.412. On follow-up, there was no significant differ- ence between the studied groups concerning postoperative complications.     
Conclusion: Prophylactic antibiotics before the surgical in- tervention of first-trimester miscarriage resulted in an insig- nificant decrease in postoperative pelvic infection.
Keywords
prophylactic antibiotics; pelvic infection; first-trimester miscarriage
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