Abd El-Alim, A., Galal, A., Mahmoud, S., El-Sayed, W. (2017). Comparative ameliorative effect of Hydrated sodium calcium aluminosilicate and Saccharomyces cerevisiae (Brewer's yeast) against toxic impact of aflatoxin B1 in Oreochromis niloticus (Nile tilapia). test, 45(Supplementary 1), 210-220. doi: 10.21608/zvjz.2017.28666
Abd El-Alim F. Abd El-Alim; Azza A. A. Galal; Shahira H. Mahmoud; Walaa A. El-Sayed. "Comparative ameliorative effect of Hydrated sodium calcium aluminosilicate and Saccharomyces cerevisiae (Brewer's yeast) against toxic impact of aflatoxin B1 in Oreochromis niloticus (Nile tilapia)". test, 45, Supplementary 1, 2017, 210-220. doi: 10.21608/zvjz.2017.28666
Abd El-Alim, A., Galal, A., Mahmoud, S., El-Sayed, W. (2017). 'Comparative ameliorative effect of Hydrated sodium calcium aluminosilicate and Saccharomyces cerevisiae (Brewer's yeast) against toxic impact of aflatoxin B1 in Oreochromis niloticus (Nile tilapia)', test, 45(Supplementary 1), pp. 210-220. doi: 10.21608/zvjz.2017.28666
Abd El-Alim, A., Galal, A., Mahmoud, S., El-Sayed, W. Comparative ameliorative effect of Hydrated sodium calcium aluminosilicate and Saccharomyces cerevisiae (Brewer's yeast) against toxic impact of aflatoxin B1 in Oreochromis niloticus (Nile tilapia). test, 2017; 45(Supplementary 1): 210-220. doi: 10.21608/zvjz.2017.28666

Comparative ameliorative effect of Hydrated sodium calcium aluminosilicate and Saccharomyces cerevisiae (Brewer's yeast) against toxic impact of aflatoxin B1 in Oreochromis niloticus (Nile tilapia)

Zagazig Veterinary Journal
Article 22, Volume 45, Supplementary 1, October 2017, Pages 210-220    PDF (272.92 K)
Document Type: Original Article
DOI: 10.21608/zvjz.2017.28666
Authors
Abd El-Alim F. Abd El-Alim1; Azza A. A. Galal* 1; Shahira H. Mahmoud2; Walaa A. El-Sayed2
1Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt
2Animal Health Research Institute, Zagazig Branch, Zagazig 44516, Sharkia, Egypt
Abstract
Different ways have been used in an attempt to decrease the risk of aflatoxicosis in fish. This study was undertaken to compare the possible alleviative effects of hydrated sodium calcium aluminosilicate (HSCAS) and Saccharomyces cerevisiae against the toxic impact of aflatoxin B1 (AFB1) on Oreochromis niloticus (O. niloticus). Therefore, 180 normal cultured monosex O. niloticus were randomly allocated into 6 equal groups. Group 1, was received the basal ration only. Group 2, was fed a basal ration supplemented with 0.5% HASCAS. Group 3, was fed a basal diet enriched with 0.25% Saccharomyces cerevisiae. Group 4, was received a diet intoxicated with 2.5 ppm aflatoxin B1. Group 5, was fed a diet intoxicated with 2.5 ppm AFB1 with 0.5% HSCAS. Group 6, was fed a diet intoxicated with 2.5 ppm AFB1 with 0.25% S. cerevisae. AFB1 intoxication induced mortality 16.67 %, leucopenia, lymphopenia, neutrophilia with a significant decrease in phagocytic % and index. Furthermore, significant increases in serum creatinine, ALT and ALP as well as a significant decrease in total protein, albumin and globulin were recorded. Moreover, accumulation of aflatoxin residues in O. niloticus flesh (5 ppb) and liver (15 ppb). While, supplementation of AFB1 intoxicated diet either with S. cerevisiae or HSCAS ameliorated the drastic effects of aflatoxin on O. niloticus and S. cerevisiae appear to be more effective in the protection of fish from aflatoxicosis than HSCAS.
Keywords
Aflatoxin B1; residues; hematology; phagocytosis; HSCAS; Saccharomyces cerevisiae
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