Curcumin provides skin Protection against UV radiation | ||
| Egyptian Journal of Chemistry | ||
| Volume 65, Issue 131, December 2022, Pages 1341-1343 PDF (236.33 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2022.140400.6150 | ||
| Authors | ||
| Ebtesam A. Mohamad* ; Monira Rageh; Haiam Ahmed | ||
| Biophysics Department, Faculty of Science, Cairo University, Egypt. | ||
| Abstract | ||
| The aim of this study is to evaluate the UV-protective activity of nano-curcumin in a rat skin model and compare its results with a commercial sunscreen agent, phenylbenzimidazole-5-sulfonic acid (PBSA). Nano-curcumin were prepared and characterized by measuring their size distribution. The photoprotective potential was evaluated by histopathological examination of the skin. Results showed that skin group irradiated with UV showed a significant histopathological change, it showed skin thickening and necrosis of dermal collagen. On the other hand, treatment with nano-curcumin protected skin tissues against UV damage by restoring histopathology changes. The results revealed that nano-curcumin provide a significant protection to the skin tissues in comparison with conventional treatment by PBSA. | ||
| Keywords | ||
| Nano-curcumin; histopathological; Skin | ||
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