Omar, B., Abou El-khier, N., Mashaly, M., Ghoneim, M., Elhadedy, M., Megahed, M., Altayyeb, M., Abdelhady, A., Raafat, D., Wadie, B. (2023). Rapid antigen test in diagnosis of SARS-COV-2 in a specialized care facility Urology and Nephrology center –Mansoura University. test, 4(2), 383-392. doi: 10.21608/mid.2023.186452.1449
Basma A Omar; Noha Tharwat Abou El-khier; Mohamed E Mashaly; Moatasem Elsayed Ghoneim; Muhammed Elhadedy; Mohamed Osama Megahed; Mohamed Altayyeb; Aml Abdelhady; Douaa Raafat; Bassem S Wadie. "Rapid antigen test in diagnosis of SARS-COV-2 in a specialized care facility Urology and Nephrology center –Mansoura University". test, 4, 2, 2023, 383-392. doi: 10.21608/mid.2023.186452.1449
Omar, B., Abou El-khier, N., Mashaly, M., Ghoneim, M., Elhadedy, M., Megahed, M., Altayyeb, M., Abdelhady, A., Raafat, D., Wadie, B. (2023). 'Rapid antigen test in diagnosis of SARS-COV-2 in a specialized care facility Urology and Nephrology center –Mansoura University', test, 4(2), pp. 383-392. doi: 10.21608/mid.2023.186452.1449
Omar, B., Abou El-khier, N., Mashaly, M., Ghoneim, M., Elhadedy, M., Megahed, M., Altayyeb, M., Abdelhady, A., Raafat, D., Wadie, B. Rapid antigen test in diagnosis of SARS-COV-2 in a specialized care facility Urology and Nephrology center –Mansoura University. test, 2023; 4(2): 383-392. doi: 10.21608/mid.2023.186452.1449

Rapid antigen test in diagnosis of SARS-COV-2 in a specialized care facility Urology and Nephrology center –Mansoura University

Microbes and Infectious Diseases
Article 6, Volume 4, Issue 2, May 2023, Pages 383-392    PDF (947.44 K)
Document Type: Original Article
DOI: 10.21608/mid.2023.186452.1449
Authors
Basma A Omar1; Noha Tharwat Abou El-khier* 2; Mohamed E Mashaly3; Moatasem Elsayed Ghoneim3; Muhammed Elhadedy4; Mohamed Osama Megahed3; Mohamed Altayyeb1; Aml Abdelhady5; Douaa Raafat6; Bassem S Wadie7
1Microbiology specialist, Microbiology laboratory, Urology and Nephrology Centre, Mansoura University.
2Faculty of Medicine, Mansoura University
3Nephrology specialist, Nephrology department, Urology and Nephrology Center, Mansoura University
4Nephrology specialist, Nephrology department, Urology and Nephrology Center, Mansoura University.
5Nursing specialist, Infection control unit, Urology and Nephrology Center, Mansoura University.
6Professor of Clinical pathology, Clinical pathology department, Mansoura University.
7Professor of Urology, Director of Urology and Nephrology Center, Mansoura University.
Abstract
Background:  Polymerase chain reaction (PCR) is the benchmark in diagnosing of corona virus disease. It takes at least 4 hours. Multiple studies reported that rapid antigen test could be used. Their role in diagnosing corona virus disease 2019 (COVID-19) is questionable. This study was conducted to assess the accuracy of rapid antigen test in Urology and Nephrology Center Mansoura University, Egypt. Methods: COVID-19 rapid ag test was evaluated in comparison to real time PCR as a gold standard in diagnosis of COVID-19 infection in employees and patients with respiratory symptoms in specialized care facility Urology and Nephrology Center of Mansoura University from March2020 till August 2021. Complete blood picture and non-contrast computerized tomography (CT) was done. Results: Eight hundred and eighty-four (884) individuals (median age 36 years) were included in this study: 478 healthcare workers, 217 non-healthcare workers, and 189 patients. PCR was positive in 569 samples and negative in 315. Out of 315 negative PCR samples, 8 were positive by rapid antigen test with a specificity of 97.4%. Conclusion: Rapid antigen tests in comparison to PCR test have a good accuracy in diagnosis in of COVID-19 infection and can be used during pandemics in low-resource areas.
Keywords
COVID 19; Rapid antigen test; PCR
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