khadidja, F., nasser, B., djahida, A., Ammam, A., Reda, B., dalila, G., kheira, B. (2022). Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria. test, 14(2), 473-479. doi: 10.21608/eajbsz.2022.290569
Fyad khadidja; Belboukhari nasser; Aici djahida; Abdelkader Ammam; Belmamoun Ahmed Reda; Ghouti dalila; Boukabene Fouzia kheira. "Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria". test, 14, 2, 2022, 473-479. doi: 10.21608/eajbsz.2022.290569
khadidja, F., nasser, B., djahida, A., Ammam, A., Reda, B., dalila, G., kheira, B. (2022). 'Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria', test, 14(2), pp. 473-479. doi: 10.21608/eajbsz.2022.290569
khadidja, F., nasser, B., djahida, A., Ammam, A., Reda, B., dalila, G., kheira, B. Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria. test, 2022; 14(2): 473-479. doi: 10.21608/eajbsz.2022.290569

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

Egyptian Academic Journal of Biological Sciences, B. Zoology
Volume 14, Issue 2, December 2022, Pages 473-479    PDF (508.41 K)
Document Type: Original Article
DOI: 10.21608/eajbsz.2022.290569
Authors
Fyad khadidja1; Belboukhari nasser1; Aici djahida2; Abdelkader Ammam3; Belmamoun Ahmed Reda4; Ghouti dalila3; Boukabene Fouzia kheira5
1Laboratory of Bioactive Molecules and Chiral Separation (LMBSC) University of Bechar, Bechar, Algeria.
2Department of Exact Sciences, Normal Higher School, Bechar- 08000, Algeria.
3Laboratory of Pharmacognosy, Bio toxicology, and Biological Valorization of Plants, Moulay Tahar University, BP 20000, Saida, Algeria.
4Laboratory of Process, materials and environmental engineering, Djillali Liabes University, BP 22000, Sidi-Bel-Abbes, Algeria.
5Laboratory of Animal Production Sciences and Techniques, Mostaghanem; Moulay Tahar University, BP 20000, Saida, Algeria.
Abstract
Anvillea radiata is used in traditional medicine for the treatment of chest colds, indigestion, and gastrointestinal disorders. Our plant has hypoglycaemic, antitumor, anti-inflammatory, and antibacterial activity and is used for the treatment of dysentery.
            We have investigated the analgesic and anti-inflammatory activity of the aqueous extract of Anvillea radiata. In analgesic activity, we have used mice of the strain NMRI Albinos, weighing between 26 and 38 g (in vivo study). Acetic acid was used to induce writhes in mice, and the evaluation of the analgesic activity shows that the aqueous extract at 150 mg/kg of our plant induces a decrease in the number of abdominal cramps caused by 1% acetic acid. The aqueous extract of our plant has an analgesic effect almost equal to that of Diclofenac; in fact, the latter causes a pain inhibition of 30.28 1.1% and that of Anvillea radiata of 28.71  2.1% for a concentration of 150 mg/ kg. Our results of this research indicated that Anvillea radiata inhibited inflammation, which could explain its use in traditional medicine.
Keywords
Anvillea radiata; analgesic activity; anti-inflammatory activity; aqueous extract
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