Optical Coherence Tomography Angiography (OCTA) findings in patients with ocular hypertension | ||
| Benha Journal of Applied Sciences | ||
| Article 22, Volume 7, Issue 11, November 2022, Pages 127-134 PDF (574.05 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2022.293878 | ||
| Authors | ||
| M.M. Abdel Kader; M.H. El hatew; T.I. Mahmoud | ||
| Ophthalmology, Dept., Faculty of Medicine, Benha Univ., Benha, Egypt | ||
| Abstract | ||
| Purpose: Using optical coherence tomography angiography, we will evaluate normal people and patients with ocular hypertension regarding optic disc perfusion and peripapillary RNFL thickness (OCTA). Methods: This research involved twenty patients diagnosed with ocular hypertension (the hypertensive group) and twenty healthy volunteers (the control group). The optic nerve head was the focus of a 4.5 mm by 4.5 mm rectangle scan in each eye. Peripapillary vessel density and RNFL thicknesses were determined. Results: The average ages of those in the control group were 46.5% while those in the hypertensive group were 48.7%. The average IOP in the hypertension group was 23 mm Hg, compared to 15.6 mm Hg in the control group. Patients with ocular hypertension had decreased optic disc perfusion and RNFL thickness in the total peripapillary, superior hemi, inferior hemi, superior, inferior, nasal, and temporal quadrants (P 0.001, 0.001, 0.001, 0.001, 0.001, 0.001, 0.001, and 0.001 for each comparison, respectively) compared to healthy controls. Moreover, in patients with ocular hypertension, there was a negative correlation between IOP and optic disc perfusion across all peripheries (r= -0.625, P=0.003), the superior hemisphere (r= -0.581, P=0.007), the inferior hemisphere (r=-0.644, P=0.002), the superior quadrant (r=-0.762, P0.001), the inferior quadrant (r=-0.697, P=0.001) Total peripapilary (r = -0.717, P 0.001), superior hemi (r = -0.644, P = 0.002), inferior hemi (r = -0.745, P 0.001), superior quadrant (r = -0.677, P = 0.001), inferior quadrant (r = -0.757, P 0.001), inferior quadrant (r = -0.596, P = 0.006), and nasal quad Conclusion. In patients with ocular hypertension, OCTA may be used to evaluate vascular density in the peripapillary area and to detect changes in optic disc perfusion and RNFL thickness at their earliest stages. | ||
| Keywords | ||
| Retinal nerve fiber layer; Optical coherence tomography angiography | ||
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