Usage of Trifluoperazine Hydrochloride as Colorimetric Reagent for Quantitative Assay of Sulfamethoxazole Drug and Applications on Different Some Infection Treatment Preparations | ||
| Egyptian Journal of Microbiology | ||
| Volume 57, Issue 1, 2022, Pages 89-99 PDF (1.9 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejm.2023.181202.1223 | ||
| Authors | ||
| Haydar S.M. AL-Hujaimi1; Mohauman M. AL- Rufaie* 1; Zahraa M.M. Alrufaie2 | ||
| 1Department of Chemistry, Faculty of Science, Kufa University, Najaf, Iraq | ||
| 2) Pediatric Department, College of Medicine, Jabir ibn Hayyan Medical University, , Najaf, Iraq | ||
| Abstract | ||
| Sulfamethoxazole (SMS) was determined using a straightforward, quick, and sensitive spectrophotometric approach that was described, the method is centered on the development of a stable water-soluble a product that maximum absorption at 515 nm by Trifluoperazine hydrochloride's oxidative coupling reaction (TRF) and (SMS) utilizing nitrate cerium ammonium (CAN) acting as the oxidizing agent in a medium of acidic. Depending on the concentration of SMS, the law of beer was the concentration of range of 2-38g.ml-1and a molar absorptivity of 1.47 x 103 L.mol-1.cm-1, one that is related of -0.026 to +5.5, and in a concentration, Beer's law is applied. a relative standard deviation was 0.136 to 0.319%.the sensitivity of Sandell's was 0.172 g.cm-1 and the limit of detection (LOD) were 0.645 g/ml-1 and (LOQ) were 2.15 g/ml-1 The suggested approach has been effectively used to determine SMS in several. | ||
| Keywords | ||
| Antibacterial activity; Colorimetric assay; Spectrophotometric method; Sulfamethoxazole; Trifluoperazine hydrochloride | ||
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