El Kwas, M., Bayoumy, M., Hosny, M. (2023). Evaluation of Glutathione Levels in Saliva and Gingival Crevicular Fluid in Diabetic Patients with Chronic Periodontitis before and after Non-Surgical Periodontal Therapy. test, 26(2), 219-227. doi: 10.21608/ajdsm.2021.94029.1235
Mohamed Nabil El Kwas; Mohamed Mohamed Bayoumy; Mostafa Mohamed Hosny. "Evaluation of Glutathione Levels in Saliva and Gingival Crevicular Fluid in Diabetic Patients with Chronic Periodontitis before and after Non-Surgical Periodontal Therapy". test, 26, 2, 2023, 219-227. doi: 10.21608/ajdsm.2021.94029.1235
El Kwas, M., Bayoumy, M., Hosny, M. (2023). 'Evaluation of Glutathione Levels in Saliva and Gingival Crevicular Fluid in Diabetic Patients with Chronic Periodontitis before and after Non-Surgical Periodontal Therapy', test, 26(2), pp. 219-227. doi: 10.21608/ajdsm.2021.94029.1235
El Kwas, M., Bayoumy, M., Hosny, M. Evaluation of Glutathione Levels in Saliva and Gingival Crevicular Fluid in Diabetic Patients with Chronic Periodontitis before and after Non-Surgical Periodontal Therapy. test, 2023; 26(2): 219-227. doi: 10.21608/ajdsm.2021.94029.1235

Evaluation of Glutathione Levels in Saliva and Gingival Crevicular Fluid in Diabetic Patients with Chronic Periodontitis before and after Non-Surgical Periodontal Therapy

Al-Azhar Journal of Dental Science
Article 5, Volume 26, Issue 2, April 2023, Pages 219-227    PDF (982.92 K)
Document Type: Original Article
DOI: 10.21608/ajdsm.2021.94029.1235
Authors
Mohamed Nabil El Kwas* 1; Mohamed Mohamed Bayoumy2; Mostafa Mohamed Hosny2
1Department of Oral Medicine, Periodontology, Diagnosis and Oral Radiology
2Department of Oral Medicine, Periodontology, Oral Radiology and Oral Diagnosis Faculty of Dental Medicine (Boys – Cairo) Al-Azhar University
Abstract
Objective: the objective of this study was designed to evaluate the effect of non-surgical periodontal therapy on glutathione levels in saliva and gingival crevicular fluid among diabetics with chronic periodontitis. Subjects and methods A total number of 60 patients were selected consists of three groups: group 1 was 20 patients with healthy periodontal condition, group 2 was 20 patients with chronic periodontitis and group 3 was 20 diabetic patients with chronic. Scaling, root planning and oral hygiene instructions were performed for patients in group 2 and group 3.Saliva and GCF samples were collected from each subjects at baseline (before treatment) , one month and three months after performing the non –surgical periodontal therapy .Results Following non-surgical therapy, glutathione levels in diabetic and chronic periodontitis groups improved significantly when compared to base line levels.No significant correlation between glutathione, age and disease activity in diabetic & periodontitis groups. Conclusion Glutathione levels should be considered a marker for disease and the concentration of reactive oxygen species in human body and an important indicator for the progression of the periodontal treatment in patients with periodontal disease.
Keywords
Glutathione; Periodontitis; Diabetic Patients
Statistics
Article View: 151
PDF Download: 169