EFFECTS OF LONG-TERM TREATMENT WITH AN INHALED CORTICOSTEROID ON PHYSICAL DEVELOPMENT AND PULMONARY FUNCTION IN ASTHMATIC CHILDREN | ||
| Al-Azhar Journal of Pediatrics | ||
| Article 9, Volume 26, Issue 2, April 2023, Pages 3383-3394 PDF (143.48 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/azjp.2023.297311 | ||
| Abstract | ||
| Background: Chronic airway inflammation is a common characteristic of the diverse illness known as asthma. During the last two decades, the prevalence of childhood asthma has significantly grown. More people are using inhaled corticosteroids to treat pediatric asthma as a maintenance measure. Aim of the study: To assess the long-term impacts of inhaled corticosteroids on the physical development and pulmonary functions of asthmatic children. Subjects and methods: This study had been done at Pediatric Allergy& immunology unit at Sayed Galal University Hospital in the period from November 2021 till October -2022. Our study was carried out on 120 patients who were diagnosed with bronchial asthma according to GINA-2022 and they divided into two groups: 1. Group 1: includes 80 patients with mild and moderate bronchial asthma receiving low dose (200 mcg /day beclometasone inhaled ICS 2. Group 2: included 40 patients with severe bronchial asthma receiving high dose (400mcg/day) beclometasone inhaled ICS. Results: There was a statistically Significant differences between the two groups regarding to Respiratory score, FEV1 /FVC. Regarding physical development, there was no statistical Significant differences between the two groups. Conclusion: the present study showed that the long-term use of ICS has no significant effect on physical development of asthma patients & the use of high dose ICS was linked with better improvement in pulmonary functions compared to low dose. | ||
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