Karkour, T., Abdel-Fattah, E., Abd EL Aziz Ibrahim, T., Karawya, A. (2023). MAGNESIUM SULFATE EFFECT ON FETAL CEREBROPLACENTAL DOPPLER INDICES IN CASES OF THREATENED PRETERM LABOUR. test, 5(2), 13-14. doi: 10.21608/alexpo.2023.210378.1610
TAREK Abdelzaher Karkour; Eman Ali Abdel-Fattah; Tamer Mohamed Abd EL Aziz Ibrahim; Amira Saad Mohammed Karawya. "MAGNESIUM SULFATE EFFECT ON FETAL CEREBROPLACENTAL DOPPLER INDICES IN CASES OF THREATENED PRETERM LABOUR". test, 5, 2, 2023, 13-14. doi: 10.21608/alexpo.2023.210378.1610
Karkour, T., Abdel-Fattah, E., Abd EL Aziz Ibrahim, T., Karawya, A. (2023). 'MAGNESIUM SULFATE EFFECT ON FETAL CEREBROPLACENTAL DOPPLER INDICES IN CASES OF THREATENED PRETERM LABOUR', test, 5(2), pp. 13-14. doi: 10.21608/alexpo.2023.210378.1610
Karkour, T., Abdel-Fattah, E., Abd EL Aziz Ibrahim, T., Karawya, A. MAGNESIUM SULFATE EFFECT ON FETAL CEREBROPLACENTAL DOPPLER INDICES IN CASES OF THREATENED PRETERM LABOUR. test, 2023; 5(2): 13-14. doi: 10.21608/alexpo.2023.210378.1610

MAGNESIUM SULFATE EFFECT ON FETAL CEREBROPLACENTAL DOPPLER INDICES IN CASES OF THREATENED PRETERM LABOUR

ALEXMED ePosters
Article 1, Volume 5, Issue 2, April 2023, Pages 13-14
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2023.210378.1610
Authors
TAREK Abdelzaher Karkour1; Eman Ali Abdel-Fattah2; Tamer Mohamed Abd EL Aziz Ibrahim2; Amira Saad Mohammed Karawya* 2
1Obstetrics and Gynaecology department, Faculty of Medicine, Alexandria University, Alexandria, Egypt
2Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University
Abstract
Introduction:

Preterm labor is one of the commonest clinical events where traditional pregnancy can turn into a high risk situation for the mother as well as the fetus. Magnesium sulfate (MgSO4), which is a calcium antagonist, has been used for over 30 years as short-term treatment (less than 48 h) for acute preterm labor. It acts by inhibiting voltage independent calcium channels in the myometrial cell surface. Extracellular magnesium suppresses calcium influx across cell membranes, whereas intracellular magnesium competes with calcium, there by inhibiting myosin light-chain kinase activity.

Aim of the Work:
The aim of the study was to evaluate the effect of magnesium sulfate administration on cerebroplacentalratio (CPR) assessed by Doppler ultrasound incases of threatened preterm labor.

Patients and Methods:
The study included one hundred ten pregnant women. All patients (n=110) underwent complete history taking, clinical examination, ultrasound examination for fetal biometry ,mean gestational age and color Doppler examination.
Keywords
MAGNESIUM; PRETERM; LABOUR; CEREBROPLACENTAL
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