The Prevalence of Osteoporosis in Chronic Liver Disease Patients Seen in Basrah Gastroenterology and Hepatology Hospital | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 147, Volume 91, Issue 1, April 2023, Pages 4707-4711 PDF (607.61 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2023.299487 | ||
| Authors | ||
| Kamal Breesam Lafta; Muntadher Abdulkareem Abdullah* ; Fatih A. Al Khaqani; Akeel M. Jaber | ||
| Abstract | ||
| Background: Osteoporosis (OP) has become an increasingly recognized complication among patients with chronic liver disease (CLD). Objective: This study aimedto determine the prevalence of osteoporosis among patients with CLD and to identify the risk factors associated with osteoporosis in these patients. Materials and Methods: One hundred patients who visited Basrah Gastroenterology and Hepatology Hospital between February 2020 and December 2021 with assessed osteoporosis. Using dual energy X-ray absorptiometry (DEXA), bone density was evaluated. The severity of liver disease, smoking, alcohol use, demographic, biochemical characteristics were all taken while assessing the risk factors for osteoporosis. Results: Of the 100 patients (male/female: 44%/56%, mean age (46 ± 11.5), 50% had CLD diagnoses, 50% did not. Of the 50 patients with CLD,20 patients had OP(40%),while four patients (8%) of the 50 patients without CLD had OP. Twenty-four (24%) of the total patients who undertook the DEXA study showed OP, while seventy-six (76%) did not. Twenty of the twenty-four individuals with OP had CLD (84%) while just four (16%) did not. Child-Pugh A made up 26% of CLD patients, Child-Pugh B 30%, while Child-Pugh C 44%. In this study, osteoporosis and osteopenia were present at rates of 24% and 31% respectively. OP and CLD appeared to be related in a very substantial way (p 0.001). CLD was identified as an independent predictor of OP by multivariate logistic regression analysis (OR (95% CI):9.09(2.18-37.93), p=0.0 Conclusion: It was determined that OP and CLD are significantly correlated. People with CLD were more likely to develop OP. As a result, routine follow-up of these individuals may require biochemical and bone mineral density (BMD) monitoring. | ||
| Keywords | ||
| Osteoporosis; Chronic liver disease; CLD; DEXA scan | ||
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