A. El Maksoud, H., Mahrous, U., El-far, A., Sadek, K., Ajaj, A. (2017). Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction. test, 4(1), 27-35. doi: 10.21608/sjou.2017.30463
Hussein A. El Maksoud; Usama E. Mahrous; Ali H. El-far; Kadry M. Sadek; Al-Hossain H. Ali Ajaj. "Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction". test, 4, 1, 2017, 27-35. doi: 10.21608/sjou.2017.30463
A. El Maksoud, H., Mahrous, U., El-far, A., Sadek, K., Ajaj, A. (2017). 'Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction', test, 4(1), pp. 27-35. doi: 10.21608/sjou.2017.30463
A. El Maksoud, H., Mahrous, U., El-far, A., Sadek, K., Ajaj, A. Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction. test, 2017; 4(1): 27-35. doi: 10.21608/sjou.2017.30463

Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction

Scientific Journal of October 6 University
Article 4, Volume 4, Issue 1, July 2017, Pages 27-35    PDF (317.86 K)
Document Type: Original Article
DOI: 10.21608/sjou.2017.30463
Authors
Hussein A. El Maksoud1; Usama E. Mahrous2; Ali H. El-far3; Kadry M. Sadek3; Al-Hossain H. Ali Ajaj4
1Biochemistry Department, Faculty of Vet. Med. Moshtohor, Benha University, Egypt
2Biochemistry Department, Faculty of Vet. Med. Moshtohor, Benha University, Egypt.
3Animal and Poultry Behavior, Faculty of Vet. Med. Damnhour University, Egypt
4Lectuerer of Biochemisry, Faculty of Vet. Med. Damnhour University, Egypt.
Abstract
The present study was designed to evaluate the protective effect and treatment effect of Alpha lipoic acid administration on cardiac necrosis markers, some electrolytes and cardiac tissue antioxidants in myocardial necrosis induced experimentally in rats- The investigated serum and cardiac biochemical parameters were: A) Serum levels of creatine kinase (CK) ,creatine kinase MB (CK-MB), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), total protein (T.P), albumin (Alb), glucose, calcium (Ca), sodium (Na), potassium (K), phosphorus (P). B) RBCs glucose 6 phosphate dehydrogenase (G-6-PDH). C) Cardiac antioxidants (SOD and CAT) and cardiac oxidant (MDA).
Keywords
Alpha – Lipoic Acid; Oxidative Stress; Myocardial Infarction and calcium
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