Periodontal wound healing with hyaluronic acid alone or in conjunction with bovine bone graft in the treatment of class II furcation defects: A histologic and histomorphometric study | ||
| Egyptian Dental Journal | ||
| Volume 69, Issue 3, July 2023, Pages 1963-1978 PDF (3.54 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2023.208366.2537 | ||
| Authors | ||
| Ghada Bassiouny* 1; Tarek Alsahry1; Samia Soliman2 | ||
| 1Associate Professor, Department of Periodontology, Oral medicine and diagnosis, faculty of Dentistry Alexandria University, Egypt | ||
| 2Professor, Department of Oral Biology, faculty of Dentistry Alexandria University, Egypt | ||
| Abstract | ||
| Aim: The goal of the current study was to evaluate the periodontal wound healing potential of hyaluronic acid alone or in conjunction with bovine bone graft in the treatment of canine class II furcation defects. Materials and Methods: In beagle dogs, class II furcation defects were surgically made in the mandibular premolars. Both open flap debridement (OFD) and hyaluronic acid (HA) were used to address the deficiencies in the HA group and OFD plus hyaluronic acid (HA) and bovine bone graft (BG) in the HA/BG group. The animals were euthanized at 12 weeks to allow for histological analysis. Results: The newly formed bone height in the HA group was (3.94 ± 0.28 mm) and in HA/BG (4.19 ± 0.37mm), the newly formed bone percentage in the HA group was (73.75 ±6.28) and in HA/BG group was (76.26 ±6.49) and the thickness of the newly formed bone trabeculae in HA group was (0.38 ±0.04) and in HA/BG was (0.47 ±0.06). Statistical analysis showed no significant differences in any of the histomorphometric measures between the HA and HA/BG at (p < 0.05) except for the thickness of the newly formed bone trabeculae that significantly increased in HA/BG group in comparison to HA group (p = 0.013). Conclusions: Within their limitations, the findings of the current study imply that using HA alone or in conjunction with BG promotes periodontal wound healing in surgically induced class II furcation defects. | ||
| Keywords | ||
| bone graft; furcation defects; hyaluronic acid; periodontal wound healing | ||
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