PHYSIOLOGICAL STUDIES OF HONEYBEE PRODUCT (PROPOLIS) ON IMMUNITY AND SOME HAEMATOLOGICAL PARAMETERS IN MALE RATS | ||
| Journal of the Egyptian Veterinary Medical Association | ||
| Volume 79, Issue 2, June 2019, Pages 387-402 PDF (745.96 K) | ||
| Document Type: Original Research Articles | ||
| Abstract | ||
| Propolis or bee glue is one of the most powerful hive products of honeybees. It is considered an important natural dietary supplement. The present study aimed to clarify the physiological effect of propolis on immunity and some haematological parameters in male rats. This study was carried on 45 Wister male rats, 21 days old. The experiment lasted for 2 months; rats were equally allocated into three groups, the control group, fed on a basal diet, low dose propolis group supplemented daily with 750mg propolis/kg diet, high dose propolis group supplemented daily with 1.5 g propolis/kg diet. Whole blood and serum samples were obtained for measuring; some immunological parameters [total leucocytic count (TLC), lymphocyte and neutrophil %, lymphocyte transformation test (LTT), nitroblue tertrazolium (NBT) and total immunoglobulin G (T.IgG)], some hematological parameters [red blood cells count (RBCs),haemoglobin (Hb) and packed cell volume (PCV)].The obtained result revealed that, propolis is a powerful immunomodulatory natural product via increasing lymphocyte % and consequently increasing antibody production, also propolis improved all haematological parameters studied. Conclusively, the dietary supplementation of high dose propolis for 2 months for improvement of immunological and haematological parameters is recommended | ||
| Keywords | ||
| Propolis; immunity; haematological parameters; male rats | ||
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