El Oany, A., kadry, A., Mehany, A., Bakry, S., Fares, M. (2023). Novel Study of Testicular Volumes and Reproductive Hormones are Associated with the Infertility in Men with Non-Obstructive Azoospermia. test, 15(2), 25-36. doi: 10.21608/eajbsc.2023.308724
Ahmed El Oany; Ahmed kadry; Ahmed B. M. Mehany; Sayed Bakry; Mohamed Fares. "Novel Study of Testicular Volumes and Reproductive Hormones are Associated with the Infertility in Men with Non-Obstructive Azoospermia". test, 15, 2, 2023, 25-36. doi: 10.21608/eajbsc.2023.308724
El Oany, A., kadry, A., Mehany, A., Bakry, S., Fares, M. (2023). 'Novel Study of Testicular Volumes and Reproductive Hormones are Associated with the Infertility in Men with Non-Obstructive Azoospermia', test, 15(2), pp. 25-36. doi: 10.21608/eajbsc.2023.308724
El Oany, A., kadry, A., Mehany, A., Bakry, S., Fares, M. Novel Study of Testicular Volumes and Reproductive Hormones are Associated with the Infertility in Men with Non-Obstructive Azoospermia. test, 2023; 15(2): 25-36. doi: 10.21608/eajbsc.2023.308724

Novel Study of Testicular Volumes and Reproductive Hormones are Associated with the Infertility in Men with Non-Obstructive Azoospermia

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Volume 15, Issue 2, December 2023, Pages 25-36    PDF (731.18 K)
Document Type: Original Article
DOI: 10.21608/eajbsc.2023.308724
Authors
Ahmed El Oany1; Ahmed kadry2; Ahmed B. M. Mehany3; Sayed Bakry3; Mohamed Fares3
1Medical analysis specialist at Benha Teaching Hospital، Cairo, Egypt.
2International Islamic Center for Population Studies and Research, Al-Azhar University, Cairo, Egypt.
3Department of Zoology, Faculty of Science, Al Azhar University, Nasr City 11884, Cairo, Egypt.
Abstract
The purpose of this study is to assess a potential association between reproductive hormone levels and testicular volumes with testicular biopsy in men with non-obstructive azoospermia (NOA) undergoing testicular sperm extraction (TESE). The complete records of 100 azoospermia men without clinical evidence of obstructive etiologies who underwent TESA. Preoperative diagnostic biopsies were not obtained and thus men with presumed NOA were defined as having no evidence of obstruction by history or physical examination. Preoperative FSH, LH and testosterone were obtained for all patients and bilateral testicular volume was determined to find the correlation between probabilities of positive sperm extraction with TESE. Two subgroups of NOA were evaluated (Group 1 TESE and Group 2 Fresh ejaculated). Results: There were significant differences in FSH, levels, in group 2 compared to group 1, and no significant differences in LH, PRL, Testosterone, and E2. Furthermore, no significant differences in right testicular volume, and left testicular volume in the two groups. The success rate of TESE was decreased when increased FSH and LH levels. In NOA cases increased FSH and LH levels, and decreased testis volumes have a negative effect on sperm retrieval but small testicular volumes only can present sperm retrieval.
Keywords
Azoospermia; Reproductive hormones; Testicular volume; TESE
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