Prevalence and Possible Risk Factors of Metabolic Associated Fatty Liver Disease (MAFLD) in Non-Obese Individuals in El-Minia Governorate –Egypt | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 44, Volume 92, Issue 1, July 2023, Pages 5756-5762 PDF (457.6 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2023.309006 | ||
| Abstract | ||
| Background: Obesity is a significant risk factor for metabolic associated fatty liver disease (MAFLD). It influences around 20%-30% of population worldwide and enhances the risk for hepatic and extra-hepatic complications. However, MAFLD occurs in lean subjects. Objective: This study aimed to detect the prevalence of non-obese NAFLD in our community, to compare the socio-demographics, clinical and metabolic characteristics of non-obese versus obese MAFLD individuals, and to determine risk factors for MAFLD in non-obese subjects. Materials and methods: 100 adults aged ≥18 years with BMI ≤ 25 were studied. In this study, clinical assessment, anthropometric measurements, laboratory tests, ultrasonography (US) and shear wave elastography were done. Results: Among 100 subjects, 26 were MAFLD lean, while 74 healthy controls, the lean MAFLD females were 19 (73.1%), while 7 (26.9%) were males. Lean MAFLD was more common in females, housewives with possible risk factors like insulin resistance and hyperlipidemia. Conclusion: MAFLD is present in non-obese individuals with possible risk factors like insulin resistance and hyperlipidemia. | ||
| Keywords | ||
| Dyslipidemia; Insulin resistance; Lean metabolic associated fatty liver disease | ||
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