Assessment of serum VEGF level in children type 1 diabetes mellitus | ||
| Minia Journal of Medical Research | ||
| Articles in Press, Accepted Manuscript, Available Online from 25 July 2023 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2023.217628.1419 | ||
| Authors | ||
| yara ihab haddad* 1; abdulhakeem abdulhakeem2; Hend mohamed moaness3; Reem Abdel-Salam4 | ||
| 1pediatrics and neonatology department, faculty of medicine, minia university, Al minia, egypt | ||
| 2pediatric and neonatology department , faculty of medicine , minia university | ||
| 3faculty of medicine minia university clinical pathology department | ||
| 4Assistant professor of pediatrics, faculty of medicine Minia University | ||
| Abstract | ||
| Abstract Background: Diabetes mellitus is a chronic metabolic disorder that affects numerous body organs and causes a variety of consequences. It is characterized by persistent hyperglycemia brought on by a problem with insulin production or by insulin resistance. Aims: The aim of this study is to assess the level of serum VEGF (Vascular endothelial growth factor) in children with type 1 DM and its correlation with glycemic control. Patient and Methods: This case-control study, was conducted on 50 children with type 1 DM (Group I) who had regular follow up in the Pediatric Endocrinology Outpatient Clinic. And controls are 20 other apparently healthy children (group II) with matched age and sex. Age: between 5 and 18 years, Duration of diabetes mellitus more than 3 years, normal A\C ratio, and normal fundus examination were included in our study. HBA1c and VEGF were done on all of the patients. Results: our results show that there is a significant positive correlation between the duration of the disease, HBA1C (P value= 0.001), duration of disease and VEGF level (p value= 0.001), HBA1C level and VEGF serum level (p value= 0,001) Conclusions: we demonstrated the significant correlation of VEGF and HbA1c and that should be done to all diabetic patients. Key words;:diabetes mellitus, HBA1C, VEGF. | ||
| Keywords | ||
| Key words; diabetes mellitus, HBA1C, VEGF | ||
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