HISTOPATHOLOGICAL AND BIOCHEMICAL STUDIES OF SOME ORGANS OF MALE ALBINO RAT FOLLOWING CHRONIC ADMINISTRATION OF BENZENE | ||
| Bulletin of Faculty of Science, Zagazig University | ||
| Article 18, Volume 2017, Issue 1, 2017, Pages 305-316 PDF (457.76 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfszu.2017.31056 | ||
| Authors | ||
| EL-Sayed Nasr1; Fawzia Goweder2 | ||
| 1Zoology Depart., Fac. of Sci., Zagazig Univ., Egypt | ||
| 2Zoology Depart., Fac. of Sci., Sabratha Univ., Libya | ||
| Abstract | ||
| The present study was aimed to investigate the possible biochemical and histopathological effects of benzene on the liver and kidney of male albino rat. Hepatic and renal indices such as alanine and aspartate aminotransferases and alkaline phosphatase, as well as creatinine, urea and uric acid were used as markers of study. Biochemical estimation of hepatic enzymes and renal indices were significantly increased compared to control and confirmed the histopathological results which showed both hepatic and renal damage. It b concluded that the ingestion of benzene-contaminated food showed a deleterious effect the liver and kidney at the employed doses and for the use period | ||
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