Helal, E., El-Aleem, M., Ahmed, S. (2019). Comparison between Sesame Oil and Glycyrrhizaglabra Effect as Phytoestrogen on Male Albino Rats. test, 75(4), 2550-2555. doi: 10.21608/ejhm.2019.31084
Eman G.E. Helal; Mohamed A. El-Aleem; Shaimaa S. Ahmed. "Comparison between Sesame Oil and Glycyrrhizaglabra Effect as Phytoestrogen on Male Albino Rats". test, 75, 4, 2019, 2550-2555. doi: 10.21608/ejhm.2019.31084
Helal, E., El-Aleem, M., Ahmed, S. (2019). 'Comparison between Sesame Oil and Glycyrrhizaglabra Effect as Phytoestrogen on Male Albino Rats', test, 75(4), pp. 2550-2555. doi: 10.21608/ejhm.2019.31084
Helal, E., El-Aleem, M., Ahmed, S. Comparison between Sesame Oil and Glycyrrhizaglabra Effect as Phytoestrogen on Male Albino Rats. test, 2019; 75(4): 2550-2555. doi: 10.21608/ejhm.2019.31084

Comparison between Sesame Oil and Glycyrrhizaglabra Effect as Phytoestrogen on Male Albino Rats

The Egyptian Journal of Hospital Medicine
Article 3, Volume 75, Issue 4, April 2019, Pages 2550-2555    PDF (408.42 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.31084
Authors
Eman G.E. Helal* 1; Mohamed A. El-Aleem2; Shaimaa S. Ahmed1
1Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt
2Physiology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Abstract
Background: Phytoestrogen is a plant-derived compound, which has estrogenic effect and it is found in liquorice root extract and sesame oil.Aim of the work:To investigate some biochemical effects of liquorice root extract and sesame oil on male albino rats. Materials and methods: 18 animals were divided randomly into three groups. Group A: Control group, group B: rats treated with oral dose of liquorice10 mg/kg body weight/day for one month, andgroup C: rats treated with oral dose of sesame oil 1 ml/kg body weight/day. At the end of the experiment, blood samples were collected for biochemical analysis. Results: Liquorice and sesame oil induced highly significant decrease in TC, TG, LDL, VLDL, LDL/HDL(p<0.01)and significant increase in HDL(p<0.05). They also showedhighly significantly decrease in FSH, testosterone and sperm countcompared to control group(p<0.01). Conclusion:The study supports that the high level intake of liquoriceroot extract orsesame oil caused hormonal disturbance and decreases sperm count.
Keywords
Liquorice root; Sesame oil; Lipid profile; albino rats; physiological parameters
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