Coagulation Profile in COVID-19 Patients | ||
| Minia Journal of Medical Research | ||
| Articles in Press, Accepted Manuscript, Available Online from 08 August 2023 | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjmr.2023.222077.1455 | ||
| Authors | ||
| martha nady khalel* 1; Ashraf Osman2; Ayman Gameel Ghobrial3; dalia abdelrahman meshref1 | ||
| 1faculty of medicine minia universty | ||
| 2Department of Clinical Pathology, El-Minia Faculty of Medicine | ||
| 3Clinical pathology department, Faculty of medicine, Minia Univerisity | ||
| Abstract | ||
| Purpose of study: Coronavirus disease-2019 (COVID-19) is an infectious illness caused by coronavirus-2 (SARS-CoV-2) that results in a severe acute respiratory syndrome. The hallmark of COVID-19 is thromboembolic consequences, which can result in death even in COVID-19 individuals who are asymptomatic Aim and objectives: This study aimed to evaluate activated partial thromboplastin time(aPTT) ,International normalized ratio (INR) and D-dimer in COVID-19 patients and their association in COVID-19 coagulopathy . Basic procedures: The study was conducted on 54 subjects including 16 apparently healthy individuals (group II) with matched age and sex as a control group and 38 patients diagnosed having covid 19 infection by PCR , level of aPTT , INR and D-dimer were measured . Main findings: results of this study revealed that there was statistically significant increase in aPPT , INR and D-dimer in the COVID-19 patients when compared to the control group. Principle conclusion: Overall Coagulopathy is a serious complication . Therefore, markers of coagulation aPTT, INR and D-dimer are useful determinig and predicting fate of COVID-19 . | ||
| Keywords | ||
| aPTT; INR; D-dimer; coagulation; COVID-19 | ||
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