KAMAL, S., WAHED, A., ABDELHAKAM, S., DABBOUS, H., FAHIM, N., GHORABA, D. (2023). ROLE OF ERCP IN MANAGEMENT OF BACTERIAL CHOLANGITIS IN LIVING-DONOR LIVER TRANSPLANT RECIPIENTS WITH BILIARY COMPLICATIONS: A SINGLE CENTER STUDY. test, 53(2), 219-225. doi: 10.21608/jesp.2023.312104
SANAA MOHARRAM KAMAL; AHMED NAGAH BASSIONY ABDEL WAHED; SARA MAHMOUD ABDELHAKAM; HANY MANSOUR KHALIL DABBOUS; NOHA ALAA ELDIN MOHAMMED FAHIM; DALIA GHORABA. "ROLE OF ERCP IN MANAGEMENT OF BACTERIAL CHOLANGITIS IN LIVING-DONOR LIVER TRANSPLANT RECIPIENTS WITH BILIARY COMPLICATIONS: A SINGLE CENTER STUDY". test, 53, 2, 2023, 219-225. doi: 10.21608/jesp.2023.312104
KAMAL, S., WAHED, A., ABDELHAKAM, S., DABBOUS, H., FAHIM, N., GHORABA, D. (2023). 'ROLE OF ERCP IN MANAGEMENT OF BACTERIAL CHOLANGITIS IN LIVING-DONOR LIVER TRANSPLANT RECIPIENTS WITH BILIARY COMPLICATIONS: A SINGLE CENTER STUDY', test, 53(2), pp. 219-225. doi: 10.21608/jesp.2023.312104
KAMAL, S., WAHED, A., ABDELHAKAM, S., DABBOUS, H., FAHIM, N., GHORABA, D. ROLE OF ERCP IN MANAGEMENT OF BACTERIAL CHOLANGITIS IN LIVING-DONOR LIVER TRANSPLANT RECIPIENTS WITH BILIARY COMPLICATIONS: A SINGLE CENTER STUDY. test, 2023; 53(2): 219-225. doi: 10.21608/jesp.2023.312104

ROLE OF ERCP IN MANAGEMENT OF BACTERIAL CHOLANGITIS IN LIVING-DONOR LIVER TRANSPLANT RECIPIENTS WITH BILIARY COMPLICATIONS: A SINGLE CENTER STUDY

Journal of the Egyptian Society of Parasitology
Article 4, Volume 53, Issue 2, August 2023, Pages 219-225    PDF (682.68 K)
DOI: 10.21608/jesp.2023.312104
Authors
SANAA MOHARRAM KAMAL1; AHMED NAGAH BASSIONY ABDEL WAHED1; SARA MAHMOUD ABDELHAKAM1; HANY MANSOUR KHALIL DABBOUS1; NOHA ALAA ELDIN MOHAMMED FAHIM2; DALIA GHORABA1
1Department of Tropical Medicine, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt
2Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt
Abstract
Biliary complications are still frequent after liver transplantation especially living donor liver
transplantation (LDLT). Bacterial cholangitis is a potentially life-threatening complication. Management
is based on antimicrobial therapy and surgical drainage. Bile cultures can play a role
in determining the causative agent and optimizing antibiotic therapy.
This study assessed the incidence of bacterial cholangitis among recipients of LDLT and evaluated
the role of endoscopic retrograde cholangiopancreatography (ERCP) in management of
potential biliary infection.
This study was conducted at Ain Shams Organ Transplantation Center between February
2019 and April 2022. The selected 39 LDLT recipients developed post-transplant cholangitis on
top of biliary complications. Liver function tests, imaging, ERCP were performed in all patients.
The results showed that incidence of biliary complications were 38.2%. Imaging and ERCP
findings were consistent regarding the anastomotic stricture diagnosis. Stones were detected by
ERCP in 12 patients when magnetic resonance cholangiopancreatography detected them in only
one patient. Significant improvement as regard inflammatory markers (CRP-Procalcitonin)
,liver enzymes and Total bilirubin before and after ERCP.
Keywords
Living Donor Liver Transplantation; Acute cholangitis; MRCP; ERCP
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