Pathological and biochemical studies on ochratoxicosis in balady duckling with trail of treatment | ||
| Benha Veterinary Medical Journal | ||
| Article 26, Volume 31, Issue 1, September 2016, Pages 159-166 PDF (568.75 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bvmj.2016.31244 | ||
| Authors | ||
| Abo El -Fetouh H.1; Heba A.1; Halla S.2; Ghada El Kader2; Nahed A. kamora3 | ||
| 1Histopathology, departments, Animal Health Research Institute (Zagazig branches) | ||
| 2biochemistry, departments, Animal Health Research Institute (Zagazig branches) | ||
| 3clinical pathology, departments, Animal Health Research Institute (Zagazig branches) | ||
| Abstract | ||
| A total of 100 healthy balady ducklings, one day old were divided into 4 equal groups (25 in each), Gp (1) kept as control group, Gp (2 and 3) received 0.5 mg ochratoxin/kg ration and 0.5ml antiochratoxin/liter drinking water for 30 consecutive days respectively and Gp (4) received both ochratoxin and antiochratoxin in same dose, period and route of administration. Ducklings supplemented with ochratoxin displayed significant reduction in weight gain, feed conversion rate, RBCs, WBCs, Hb, PCV, T protein albumin, globulin, T. lipid, cholesterol, triglycerides CAT and SOD, coupled with significant elevatoin in feed conversion rate, mortality rate, AST, ALT, ALP, uric acid, creatinine and MDA Ducklings received antiochratoxin showed significant increase in weight gain, RBCs, Hb, total protein, albumin Catalase and super oxide dismutase beside in signif- icant increase in PCV,WBCs, globulin, AST, ALT, ALP, uric acid and creatinine, triglycerides cholesterol and total lipid coupled with insignificant decrease in MDA and improved in feed conversion rate. Hemato-biochemical profiles and antioxidant revealed significant improvement in antiochratoxin treated duckings when compared with ochratoxinated duckings. Ochratoxin residues in liver and kidney were high at 1st day of clearance period and disappeared at 10th days of clearance period. Alteration in histological picture in internal organ in duckling received ochratoxin revealed massive degenerative changes in renal epithelial cells of proximal and distal convoluted tubules (Nephrotoxicity) and massive necrosis of some tubular epithelial cells. Beside severe hepatic damage and also lesions in the immune organs and intestine. In general, histological changes were mild in birds receiving antiochratoxin alone or with ochratoxin. It could be concluded that, ochratoxicosis in duckling resulted in poor feed intake, weight gain and feed conversion rate, had adverse effect in body weight, hemato-biochemical parameters beside decreased blood antioxidant; anti-ochratoxin improved these parameters in duck | ||
| Keywords | ||
| duckling; Ochratoxin; body weight; mortality rate; blood picture; biochemical parameters; Antioxidant enzymes; Pathology | ||
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