Optical Coherence Tomography based criteria for evaluation of Choriodal Neovascularization | ||
| Fayoum University Medical Journal | ||
| Article 5, Volume 1, Issue 2, December 2018, Pages 36-41 PDF (655.53 K) | ||
| DOI: 10.21608/fumj.2018.31294 | ||
| Authors | ||
| Mahmoud A Kamal1; Ragaii M Hatata2; Shereen H Sadek2; Sherif Salah* 3 | ||
| 1Professor of Ophthalmology and Head of ophthalmology department Faculty of Medicine – Fayoum University | ||
| 2Lecturer of Ophthalmology Faculty of Medicine – Fayoum University | ||
| 3Department of ophthalmology Faculty of Medicine – Fayoum University | ||
| Abstract | ||
| Purpose: To detect the role of optical coherence tomography in evaluation of Choriodal neovascularization in response to treatment with anti vascular endothelial growth factors (VEGF). Methods: A total of 30 eyes with treatment-naïve choriodal neovascular membrane were examined using the OCT system before treatment and after treatment with anti VEGF. Results: In treatment‐naïve CNV, The activity of CNV had been evaluated according to structural OCT by presence of Cystoid Macular Edema (CME), Subretinal Fluid (SRF) , Fibrovascular Pigment Epithelial Detachment (FPED) and macular thickening . There is gradual decrease in CMT along the treatment course with repeated intravitreal anti-VEGF injections. 50 % of CNV patients had CME at baseline which gradually decreased with repeated anti-VEFG injections and disappeared completely after the third dose, 35 % of CNV patients had SRF at baseline which gradually decreased with repeated antiVEFG injections and disappeared completely after the third dose, Only two patients had PED before treatment, which gradually decreased along the course of treatment by three doses of anti VEGF injections. Conclusion: OCT is an important modality of investigation for diagnosis of CNV and detecting activity and response with treatment with anti VEGF. | ||
| Keywords | ||
| Optical coherence tomography; choriodal neovascularization; anti VEGF; Cystiod macular edema; subretinal fluid; pigment epithelial detachment | ||
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