Exploring Cutting-Edge Topics in Oral and Maxillofacial Pathology

Dear Colleagues,

A histopathologic diagnosis is no longer confined to examining H&E slides because molecular findings have reclassified the subvariants of conventional diseases as new entities that should follow a different therapeutic intervention. However, the adoption of this intervention in Oral Pathology has been slower than in breast pathology and its sister domains. For instance, the number of molecular studies published in 2022 investigating molecular details in breast and prostate cancer exceeds 35,807. Many of these studies have examined the use of ferroptosis in cancer treatment. Yet, over the past two decades, only less than 3000 articles have considered molecular findings in oral pathology.

Therefore, we allocate this special issue to discussing newly reported entities and how they are appreciated and recognized worldwide. The topics of this special issue include, but are not limited to, the following:

• Updated perspectives on sclerosing odontogenic carcinoma
• Contrasting primordial odontogenic tumor and ameloblastic fibroma
• Unravelling non-odontogenic ameloblastomatous lesions
• Emerging insights into salivary palisading adenocarcinoma and beyond
• Subtyping carcinoma ex pleomorphic adenoma: A multifaceted approach
• Grading salivary carcinoma and abrupt high-grade transformation: Implications for prognosis
• SWI/SNF-deficient carcinomas: From molecular mechanisms to clinical relevance
• Revisiting WHO Classifications and Addressing Criticisms
• Reporting molecularly labeled subtypes of salivary gland neoplasms

This issue aims to delve into the forefront of oral and maxillofacial pathology, addressing the ongoing debates, advancements, and challenges that shape our understanding of complex diagnostic entities. Pathologists can contribute by critically evaluating the existing WHO classifications, proposing refinements based on new scientific evidence and technological advancements, and addressing criticisms to improve the accuracy and clinical utility of the classifications. All topics that have sparked debates among pathologists are solicited. Scarce relevant case reports could be accepted.

We encourage all contributors to place their relevant research articles in this forthcoming issue. Manuscripts can be submitted through our online submission system. All submitted articles will undergo a rigorous peer-review process to ensure the highest quality and integrity of the published content. The submission deadline for this special issue is November 15, 2023.

Academic Editor of the Special Issue

Dr. Sherif Y. Elnagdy

Prof. of Oral Pathology

Vice Dean, Faculty of Dentistry, HUE