EVALUATION OF CLINICAL PROFILE AND FINAL OUTCOME OF NEONATES REQUIRED MECHANICAL VENTILATION | ||
| Al-Azhar Journal of Pediatrics | ||
| Article 6, Volume 26, Issue 3, July 2023, Pages 3499-3511 PDF (194.47 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/azjp.2023.314976 | ||
| Abstract | ||
| Background: Advances in perinatal and neonatal care have decreased morbidity and mortality. Due to enhanced intensive care and robust respiratory and cardiovascular support in neonatal intensive care units (NICU), the prognosis for sick infants has improved. [Mechanical ventilation depends on the underlying condition, gestational age, birth weight, and clinical circumstances. To increase the survival of mechanically ventilated infants, it is necessary to identify and address prognostic markers. Aim: To detect the causes of morbidity and mortality in mechanically ventilated neonates and to correlate the neonatal morbidity and mortality with gestational age, birth weight and duration of MV. Patients and Methods: This study was conducted in NICU at Mansoura University Children Hospital. Our study took part from October 2021 to April 2023. The study was done on one hundred (100) neonates who needed mechanical ventilation. Results: There was significant increase in ventilator associated pneumonia (VAP) and Bronchopulmonary Disease (BPD) prevalence in non-survived neonates in comparison to survived neonates and in Septic shock & Multiple Organ Failure (MOF), Disseminated Intravascular Coagulation (DIC) and Necrotizing Enterocolitis (NEC) prevalence in non-survived neonates in comparison to survived neonates. There was no significant difference between survived and non-Survived neonates according to maternal general characteristics. Conclusion: The most common reason for neonatal ventilation was congenital heart disease, according to the study. VAP and BPD were prevalent in ventilated newborns. There was positive correlation between birth weight and gestational age improved outcomes. VAP, BPD, Septic shock, MOF, DIC, NEC, ROP grade III, and ABR were related with worse outcome. To confirm our results and identify more adverse event risk variables, we need multiple conditional study. | ||
| Keywords | ||
| Neonatal; Mechanical; Ventilation; Morbidity; Mortality | ||
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