The Role of Selenium Deficiency In Dilated Cardiomyopathy | ||
| Zagazig University Medical Journal | ||
| Article 6, Volume 26, Issue 1, January and February 2020, Pages 46-52 PDF (873.95 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/zumj.2019.12220.1211 | ||
| Authors | ||
| ghada mohammed abdellatif* 1; saed mohammed morsy2; nahed mahmmoud khater3; hanan samir ahmed4 | ||
| 1pediatric department,faculty of medicine ,zagazig university,elsharkia,Egypt | ||
| 2pediatric departement, faculty of medecine,zagazig university,Elsharkia,Egypt | ||
| 3departement of pediatric ,faculty of medicine ,zagazig university,elsharkia,Egypt | ||
| 4clinical pathology,faculty of medecine,zagazig university,elshakia,Egypt | ||
| Abstract | ||
| ABSTRACT: BACKGROUND: It has been speculated that trace elements may play a role in the pathogenesis of dilated cardiomyopathy (DCM). In the present study, we aimed to assess serum concentrations of selenium (Se) in pediatric patients with idiopathic dilated cardiomyopathy (IDC) and to evaluate the correlation between serum Se concentrations and echocardiographic parameters. SUBJECTS AND METHODS: This study included 16 patients with IDC and 16 healthy controls. Serum level of selenium was measured by ELIZA method. Echocardiographic parameters including ejection fraction and fractional shortening were measured in all patients with IDC in order to evaluate its correlation with serum Se concentrations. RESULTS: Serum concentration of Se in IDC patients was significantly lower than in healthy controls (p | ||
| Keywords | ||
| KEY WORDS: Selenium; echocardiographic parameter; idiopathic dilated cardiomyopathy | ||
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