Efficacy of Combination of Biodentine and Simvastatin as Pulp Capping Materials in Vital Pulpotomy of Primary Molars: Randomized Clinical Trial | ||
| Dental Science Updates | ||
| Article 1, Volume 4, Issue 2, September 2023, Pages 205-218 PDF (1.13 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/dsu.2023.187358.1155 | ||
| Authors | ||
| Noha Elsayed* 1; Enas M. Hegazy2; Mohamed Hashem Amin3; Mohamed Shrief Farag4; Shaimaa Mohamed Mahfouz Omer5 | ||
| 1Department of Pediatric dentistry, Preventive Dentistry and Dental Public Health, Faculty of Dentistry, Suez Canal University, Ismailia, 41522 | ||
| 2Department of Oral Biology, Faculty of Dentistry, Suez Canal University | ||
| 3Anesthesiology and radiology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt | ||
| 4Professor of Pediatric and Preventive Dentistry and Dental Public Health Faculty of Dentistry - Suez Canal University | ||
| 5Department of Pediatric dentistry, Preventive Dentistry and Dental Public Health, Faculty of Dentistry, Suez Canal University, Ismailia, 41522, Egypt | ||
| Abstract | ||
| ABSTRACT Introduction: Dental caries is a specific disease caused by long-term contact between the host, diet, and microorganisms on the tooth surface. This causes the inorganic parts of the enamel and dentin to break down. Aim: This study aimed to assess the clinical and radiological effectiveness of using Simvastatin in combination with Biodentine as a pulpotomy agent for vital primary molars. Materials and Methods: sixty primary molars in 20 children aged from 4-7 years old were selected from Outpatient Clinic of Pediatric Dentistry Department, Faculty of Dentistry, Suez Canal University and randomly allocated to three groups, Biodentine, Simvastatin and combination of Biodentine and simvastatin. All treated teeth were clinically evaluated at (1M,3Ms,6Ms,9Ms,12Ms) for presence of pain, tender on percussion, swelling/sinus or pathological tooth mobility and evaluated radiographically at (3Ms,6Ms,9Ms,12Ms) for loss of lamina dura, widening in periodontal ligament space presence of external/internal resorption or presence of periapical /furcation radiolucency. Result: The overall success rate was 100%, 5%, and 90% for Biodentine, Simvastatin, and the combination of Biodentine and Simvastatin groups, respectively. After a year of follow-up, the groups had a highly significant difference in overall success rates. Conclusion: After one year follow up Our findings demonstrated remarkable results of combination of Biodentine and simvastatin in pulpotomy of primary teeth. Therefore, combination of Biodentine and simvastatin may be considered as an effective material in pulpotomy of primary teeth because of its successful results. While Simvastatin showed failure clinically and radiographically. Clinical Trial Registration: Registered on ClinicalTrials.gov under identifier number: NCT05582317, Protocol Record 2020-293, https://clinicaltrials.gov/ct2/show/ NCT05582317. | ||
| Keywords | ||
| Biodentine; Pulpotomy; Primary teeth; Simvastatin; Biodentine & Simvastatin combination | ||
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