Hussin, D., Mahmood, A. (2023). Isolation and Diagnosis of Some Isolated Bacterial Types of Psoriasis Patients and Measurement of Some Immunological Parameters Such as Il-17 And Complements C3 and C4. test, 15(2), 411-417. doi: 10.21608/eajbsc.2023.320128
Dalida A. A. Hussin; Asmaa E. Mahmood. "Isolation and Diagnosis of Some Isolated Bacterial Types of Psoriasis Patients and Measurement of Some Immunological Parameters Such as Il-17 And Complements C3 and C4". test, 15, 2, 2023, 411-417. doi: 10.21608/eajbsc.2023.320128
Hussin, D., Mahmood, A. (2023). 'Isolation and Diagnosis of Some Isolated Bacterial Types of Psoriasis Patients and Measurement of Some Immunological Parameters Such as Il-17 And Complements C3 and C4', test, 15(2), pp. 411-417. doi: 10.21608/eajbsc.2023.320128
Hussin, D., Mahmood, A. Isolation and Diagnosis of Some Isolated Bacterial Types of Psoriasis Patients and Measurement of Some Immunological Parameters Such as Il-17 And Complements C3 and C4. test, 2023; 15(2): 411-417. doi: 10.21608/eajbsc.2023.320128

Isolation and Diagnosis of Some Isolated Bacterial Types of Psoriasis Patients and Measurement of Some Immunological Parameters Such as Il-17 And Complements C3 and C4

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Volume 15, Issue 2, December 2023, Pages 411-417    PDF (402.05 K)
Document Type: Original Article
DOI: 10.21608/eajbsc.2023.320128
Authors
Dalida A. A. Hussin1; Asmaa E. Mahmood2
1Department of Biology, College of Education, University of Samarra, Iraq.
2Department of Pathological Analysis, College Of Applied Sciences, University of Samarra, Iraq.
Abstract
80 samples were collected from patients at Samarra General Hospital / Salah Al-Din General Hospital, 60 samples from patients with skin psoriasis and 20 samples from healthy people in the period from September 2022 to January 2023 and for the ages of 2-80.
Some bacterial species associated with psoriasis patients have been isolated, the most isolated bacteria were Staphylococcus aureus, 33.3% of the 60 bacterial isolates were isolated, it isolated 18 isolates of Staph epidermidis with 30% of the total isolates and Staphylococcus hominas isolated by 15%, gram-negative isolates included 13.3% of P. aeruginosa and five isolates of E. coli (8.3%), some immune markers were compared between a group of psoriasis patients and a healthy (control) group, the estimated C3 supplement level for patients is 265.1 ± 215.77, while the rate for healthy people is 652.18 ± 102.3, it is noted that this indicator is higher in patients with psoriasis compared to healthy people, it also indicates that the estimated C4 supplement level for patients is 392.92 ± 63.7, while the rate for healthy people is 167.94 ± 38.7. It is noted that this indicator is higher in patients with psoriasis compared to healthy people, the IL-17 level of interleukin was 765.29 ± 85.4, while the rate for healthy people is 212.37 ± 39.6. It is noted that this indicator is higher in patients with psoriasis compared to healthy people, the results also showed significant differences between the levels of immune indicators between patients and healthy people at a probability level (p value = 0.05).
Keywords
Psoriasis; Bacteria; Immunomarkers; IL-17; C3; C4
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