COMPARATIVE STUDY ON THE USES OF GREEN COFFEE BEANS, ROASTED, ARABIC COFFEE FORMULA AND THEIR EXTRACTS TO REDUCE OBESITY IN MALE RATS | ||
| Menoufia Journal of Food and Dairy Sciences | ||
| Article 4, Volume 40, Issue 3, June 2015, Pages 679-714 PDF (1010.5 K) | ||
| Document Type: original papers | ||
| DOI: 10.21608/mjfds.2015.324006 | ||
| Authors | ||
| M. M. E. Ali1; Nabila Y. Mahmoud2; Fatma G. R. El Hawary2 | ||
| 1(1) Nutrition and Food Science , Home Economics, Menoufia University | ||
| 2(2) Nutrition and Food Science, Faculty of Home Economics, Al- Azhar University | ||
| Abstract | ||
| ABSTRACT: This study was conducted to investigate the effect of use of extract and powder of green coffee, roasted coffee, Arabic coffee and mix of green and roasted coffee to improve the level of serum lipid profile, high liver enzyme and renal function. Fifty four mature male albino rats weighting 150±10g were divided into two main groups; control negative group (6 rats) was fed on basal diet and control positive group (48 rats) which was fed on hyperlipidemic diet for four weeks to induce hyperlipidemia. Rats in the second main group supplements were divided into eight groups (each group consisted of 6 rats and fed on basal diet) as a following: The first group was left as a control positive , the second group fed diet containing 5 % Arabic coffee / kg in diet. The third group fed diet containing 5 % green coffee / kg in diet .The fourth group fed diet containing 5 % roasted coffee / kg in diet. The fifth group was administrated orally with 5 % Arabic coffee extract. The sixth group was administrated orally with 5 % green coffee extract, the seventh group was administrated orally with 5 % roasted coffee extract. The eighth group was administrated orally with 5 % mix of green and roasted coffee extract. Feeding experiment lasted for 28 days. Serum total cholesterol, triglycerides, lipoprotein fractions (HDLc, LDLc and VLDLc), atherogenic index (AI), liver enzymes(ALT, AST, ALP),total protein, albumin, globulin, albumin/globulin (A/G) ratio, uric acid, urea, creatinine, leptin hormone and testosterone hormone were assessed . Histopathological changes of liver, heart and testis were examined. The obtained results concluded that feeding with arabic coffee (5%), green coffee (5%) and roasted coffee (5%) improved liver , kidney functions, lipid profile, level of leptin and testosterone hormones, liver , heart and testis tissues changes. According to the results, arabic ,green and roasted coffee could be used for to improve the health situation of obese rats along with weight loss. | ||
| Keywords | ||
| Obesity; green coffee; roasted coffee; Arabic coffee; lipid profile; liver enzymes; leptin hormone; testosterone hormone and histopathological changes | ||
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