ASSOCIATION OF SERUM URIC ACID WITH METABOLIC SYNDROME COMPONENTS IN SYRIAN POPULATION | ||
| Bulletin of Pharmaceutical Sciences Assiut University | ||
| Volume 46, Issue 2, December 2023, Pages 1151-1160 PDF (569.24 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bfsa.2023.327762 | ||
| Authors | ||
| Ghufran Mohammad Jamal Hamid* 1; Iead Othman2; Sulaf Alwassouf1 | ||
| 1Department of Biochemistry and Microbiology, Faculty of Pharmacy, Al-baath University, Homs, Syria | ||
| 2Department of Physiology, Faculty of Veterinary Medicine, Hama University, Hama, Syria | ||
| Abstract | ||
| The current study aimed to investigate the correlation between serum uric acid levels and metabolic syndrome and its components in adult patients from Homs, Syria. This study included 86 subjects divided into two groups; 20 healthy controls and 66 patients with metabolic syndrome. Physical examination and blood pressure (BP) information were recorded. Serum uric acid (SUA), fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were tested. As a result, subjects with metabolic syndrome had significantly higher levels of SUA than controls (P < 0.001). Metabolic syndrome patients with hyperuricemia had higher BMI, WC, TC and LDL-C than those with normal uric acid levels (P < 0.05). Moreover, subjects with more metabolic syndrome components had higher SUA levels. On the other hand, SUA was positively correlated with WC, DBP, FBG, TG, TC and LDL-C and negatively with HDL-C (P < 0.05). Therefore, in general, elevated SUA levels appear to be positively associated with metabolic syndrome components in Syrian population | ||
| Keywords | ||
| Metabolic syndrome components; Hyperuricemia; Serum uric acid | ||
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