Effects of Maternal Dexamethasone Administration on Daily Foetal Movement Count and its Correlation with Doppler Studies and Non-Stress Test | ||
| Evidence Based Women's Health Journal | ||
| Article 3, Volume 7, Issue 1, February 2017, Pages 15-21 PDF (795.09 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ebwhj.2017.3220 | ||
| Authors | ||
| Youssef Mohamed Wahby* ; Ayman Nour Raslan; Hesham Mohamed El Ghazaly; Abdallah Yehia El Kateb | ||
| Department of Obstetrics and Gynaecology, Kasr Al-Ainy Teaching Hospital, Cairo University | ||
| Abstract | ||
| Objective: To evaluate the effect of Dexamethasone on the daily foetal movement count and whether this affects haemodynamics. Study Design: This is a cohort study involving pregnant women with a history of preterm labour, to follow up their daily foetal movement count for 5 days. Meanwhile, the non-stress test, middle cerebral and umbilical arteries Doppler indices were recorded before and after taking a designated Dexamethasone course. Each woman’s data was considered as her control. Patients and Methods: A total of 50 women with low risk, except a history of previous 1 or more preterm labour, were assigned to receive four separate injections of 6 mg Dexamethasone, each given 12 hours apart. Doppler studies and cardiotocography traces were done before and after administration. Foetal movements were counted by mothers using Sadovsky method since the first dose and 5 days later. Paired T, McNemar’s and Pearson’s correlation coefficient tests were used. Results: There were decrease in the MCA PI and RI (PI p <0.001, RI p = 0.002), increase in foetal heart rate short term variability (p = 0.016) and decrease in the foetal movement count on Day 2 (p < 0.001). Conclusion: Dexamethasone therapy affects the heart rate, haemodynamics and decreases daily foetal movement count. | ||
| Keywords | ||
| dexamethasone; Doppler; MCA; UA; Non-stress test | ||
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