INVESTIGATION OF IMMUNOLOGICAL RESPONSE OF EGYPTIAN BEE VENOM PREPARATION IN RABBITS | ||
| Journal of the Egyptian Society of Parasitology | ||
| Article 11, Volume 53, Issue 3, December 2023, Pages 499-502 PDF (661.32 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jesp.2023.331735 | ||
| Authors | ||
| ABIR A. ELFIKY1; EMAN ABDELRAHMAN ABOUOUF2 | ||
| 1Holding Company for Biological Products & Vaccines (VACSERA), Dokki, Egypt | ||
| 2Department Medical Parasitology, Faculty of medicine, Benha University, Benha, Egypt | ||
| Abstract | ||
| The repeated exposure of the immune system to bee venom as antigen leads to significant increase in immune response. In this study different immunological schedules were tried to reach maximum immunological effect with the least allergic side effect either by using and aqueous or emulsified preparation of bee venom. Three groups of male rabbits of one year old each were used for a period of four weeks. The blood samples were with drown before bee venom injection and weekly after its infection for determination of IgG and IgE. The results showed that injection of Egyptian bee venom in an aqueous form have the ability to boost the level of immune response without significant allergic reaction. | ||
| Keywords | ||
| Egyptian bee venom; Rabbits; Immunology; Allergic side effects; Human safety | ||
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