The Effect of Remote Ischemic Preconditioning on The Outcome of Elective Percutaneous Coronary Intervention | ||
| Benha Journal of Applied Sciences | ||
| Article 11, Volume 8, Issue 11, November 2023, Pages 79-86 PDF (440.4 K) | ||
| Document Type: Original Research Papers | ||
| DOI: 10.21608/bjas.2023.247368.1278 | ||
| Authors | ||
| Hesham Rasheed; Ali Attia; Ahmed Ibrahim; Ahmed Shaheen* | ||
| Cardiovascular Medicine Dept., Faculty of Medicine, Benha University | ||
| Abstract | ||
| Background: Remote In the setting of elective percutaneous coronary intervention, ischemia preconditioning (IPC) may serve as a cardioprotective approach (PCI). The purpose of this research was to determine whether or not cardiac troponin I (cTnI) levels before and after a procedure are predictive of major adverse cardiac events (MACE) in the 6-month follow-up period. The purpose of this research was to determine whether remote IPC may decrease cTnI levels, ischemic symptoms, ECG indications of ischemia, and the incidence of MACE if given before elective PCI. Methods: This Two hundred individuals with severe coronary artery stenosis who had undergone elective PCI were included in a prospective research. A subset of patients (Group A) received remote IPC in the form of blood pressure cuff inflations and deflations, whereas patients in Group B (the control group) did not. Patient characteristics, cardiac risk factors, electrocardiogram (ECG) results, lesion complexity, and major adverse cardiac events (MACE) rate were all evaluated. Results: Both groups had comparable baseline characteristics, including similar ages, sexes, cardiac risk factors, electrocardiogram (ECG) results, and lesion complexity. The incidence of unstable angina and MACE was reduced and cTnI levels were significantly lower 24 hours after PCI when remote IPC was used. Other procedural results and adverse events did not vary significantly across the groups.Conclusions: This research demonstrates that remote IPC provided prior to elective PCI has the potential to ameliorate post-procedural cardiac damage, as demonstrated by lowered cTnI levels, and may be related with a lower risk of MACE. | ||
| Keywords | ||
| Remote Major Adverse Cardiac Events; Ischemic Preconditioning; PCI; Cardiac Troponin I | ||
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