Effect of Luteal Estrogen Priming in Women with Poor Ovarian Response Ungergoing IVF Using Antagonist Protocol | ||
| The Egyptian Journal of Fertility and Sterility | ||
| Article 12, Volume 27, Issue 6 - Serial Number 11106352, November 2023, Pages 99-105 PDF (3.29 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/egyfs.2023.333784 | ||
| Authors | ||
| Noura El-Nassery* 1; Amal Shohayeb2; Mostafa Gamea2; Ahmed M Maged2; Mahmoud Soliman2 | ||
| 1Obstetrics and Gynecology Department, Cairo University, Egypt | ||
| 2Obstetrics and Gynecology Department, Cairo University, Cairo, Egypt | ||
| Abstract | ||
| Objective : to explore the benefits of the E2 priming during the luteal phase in women with poor ovarian response (POR) undergoing IVF cycles using the GnRH antagonist protocol. Methods : This randomized controlled study conducted on 100 POR underwent ICSI trial using GnRH antagonist protocol assigned to 1 group of 2. Group I included 50 women received oral E2 valerate 4 mg/day started on luteal day 21 and continued up to the 1st day of the cycle group II included 50 control women who did not receive estrogen priming. The main outcome parameter was the number of MII oocytes. Other outcomes included implantation, chemical pregnancy and clinical pregnancy rates. Results: No statistically significant difference between women in the estrogen priming group and other women regarding the retrieved oocytes number and quality, implantation, clinical pregnancy, or chemical pregnancy rates. Conclusion: estrogen priming did not increase the number of MII retrieved ova in POR. | ||
| Keywords | ||
| Keywords: Estrogen priming; Poor ovarian responders; clinical pregnancy rate; IVF | ||
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