Age related decline of male fertility (ARDMF), the other side of the coin, a review article | ||
| Journal of Reproductive Medicine and Embryology | ||
| Article 5, Volume 1, Issue 1, January 2024, Pages 26-31 PDF (250.25 K) | ||
| Document Type: Mini review | ||
| DOI: 10.21608/jrme.2024.265560.1009 | ||
| Authors | ||
| Medhat Amer1, 2, 3; Emad Fakhry* 2 | ||
| 1Andrology Department, Faculty of Medicine, Cairo University, Egypt. | ||
| 2Adam International Hospital, Cairo, Egypt. | ||
| 3Egyptian Foundation of Reproductive Medicine and Embryology (EFRE). | ||
| Abstract | ||
| Background: The effect of male age on male fertility is a debatable subject. Men never stop producing sperms, but there is a decline in sperm quality as a man ages. According to the World Health Organization (WHO) starting around the age of 35, semen parameters worsen. The sperm quality parameters naturally change with age: count, motility, morphology, DNA fragmentation, and genetic mutations. Paternal age is among the factors affecting a couple’s chance of conceiving and their pregnancy outcomes. Pregnancy Rate, time to conception, miscarriage risk, adverse pregnancy outcomes, and Offspring health risks are all affected by male age. Some studies have shown that paternal age does not affect pregnancy outcomes using conventional in vitro fertilization (IVF) techniques, while others report decreased pregnancy and live birth rates with increased male age. Objective: to discuss the effect of male aging on fertility and pregnancy outcome and also on the results of assisted reproduction. Conclusion: Male Age has a significant role in his fertility potential and would affect pregnancy prognosis as well as ART results. | ||
| Keywords | ||
| Aged male; Male fertility; Assisted reproduction | ||
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