Corneal endothelial cell loss following Deep Anterior Lamellar Keratoplasty | ||
| NILES journal for Geriatric and Gerontology | ||
| Volume 7, Issue 1, January 2024, Pages 226-236 PDF (714.01 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/niles.2024.339449 | ||
| Authors | ||
| Rasha Mohamed Mousa* 1; Khaled Gamal Ibrahem Aboulenin* 2; Nehal Maher Samy Elgendy* 2; Mahmoud Sami Mahmoud Elsayed* 1 | ||
| 1Memorial institute for ophthalmic research , Giza , Egypt | ||
| 2KasrAlainy Faculty of Medicine, Cairo University, Giza , Egypt | ||
| Abstract | ||
| Purpose: evaluating the alterations in endothelial cell density and gauge the visual results after performing deep anterior lamellar keratoplasty . Setting: Memorial institute for ophthalmic research and KasrAlainy Faculty of Medicine, Cairo University Methods: A prospective interventional study where 30 eyes from 30 patients were enrolled to undergo deep anterior lamellar keratoplasty (DALK).The technique employed either the big bubble technique or lamellar dissection . The main goal was to evaluate the variations in endothelial cell density by utilizing a non-contact specular microscope before surgery, after 6 weeks and after 6 months. Furthermore, the study also aimed to evaluate the visual outcomes measured before the surgery, at 6 weeks postoperatively, and at 6 months postoperatively. Results: Significant decrease in endothelial cell density was observed during the entire follow-up duration of the study. The preoperative cell density decreases significantly from 2905.5±119.5 to 2374.8±113.5after 6 weeks (p=0.000). Subsequently there was significant decline to 1894±113.2 at 6 months (p=0.000). Regarding visual outcome ,it showed significant improvement. Conclusion: DALK is associated with significant decrease in the endothelial cell density at 6 weeks and 6 months postoperatively and visual outcomes show significant improvement. | ||
| Keywords | ||
| keratoplasty; DALK; endothelial loss; keratoconus | ||
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