Effect of Diode Laser Irradiation and Application of Nanoparticle Herbal Endodontic Irrigation Solutions on Candida Albicans and Enterococcus Faecalis Bacteria | ||
| Egyptian Journal of Chemistry | ||
| Volume 67, Issue 13, December 2024, Pages 331-340 PDF (362.86 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejchem.2024.257353.9036 | ||
| Authors | ||
| Hesham E. Hassan1; Mohamed H. Zaazou1; Doaa M. Sadony* 1; Tarek Mohamed2 | ||
| 1Restorative and Dental Materials Department, National Research Centre, Dokki, Giza 12311, Egypt | ||
| 2Laser Institute for Research and Applications LIRA, Beni-Suef University, Beni-Suef 11345, Egypt | ||
| Abstract | ||
| The present study investigate whether diode laser activation of two nanoparticle herbal irrigants affect Enterococcus faecalis (E.faecalis) biofilm and Candida albicans (C. albicans) compared with photodynamic therapy (PDT) utilizing methelyene blue as photosensitizer (PS). Material and methods: sixty single rooted teeth had undergo mechanical preparation. Teeth were divided into 3 groups (20 teeth each), G1 : 20 teeth inoculated with Enterococcus faecalis half (n= 10) irrigated with nanocurcumin and the other half irrigated with nanoneem both activated by diode laser, G2: 20 teeth inoculated with Candida albicans irrigated similar to group 1 and G3: 10 teeth inoculated with E.faecalis and 10 with Candida albicans undergo PDT using methylene blue as PS. Results: For E.faecalis no statistically significant difference neither between nanoneem and nanocurcumin (p>0.05) nor between nanocurcumin and PDT (p>0.05). While there was a statistically significant difference between nanoneem and PDT (p<0.001). While for C. albicans no statistically significant difference between nanocurcumin and PDT (p>0.05). While the differences were statistically highly significant between nanoneem and PDT (p=0.002) and between nanoneem and nanocurcumin (p<0.001). Conclusion: nanoneem and nanocurcumin irrigants activated by laser have an effect on root canal microorganisms and could be used as adjunctive endodontic irrigant. | ||
| Keywords | ||
| Root canal irrigants; antibacterial and antifungal effect; nanocurcumin; nanoneem, photodynamic therapy | ||
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