Role of Irreversible Electroporation in Solid Abdominal Tumors Management | ||
| SECI Oncology Journal | ||
| Volume 12, Issue 1, January 2024, Pages 57-67 | ||
| Abstract | ||
| Background: Irreversible electroporation (IRE) is a new non thermal ablation modality with promise for revolutionizing the treatment for solid local tumors specially to overcome the disadvantages of other ablation maneuvers in nonsurgical cases. The study aimed to evaluate the role of irreversible electroporation as a new promising minimally invasive technique for ablation of solid abdominal tumors. Methods: 25 patients were included with unrespectable solid abdominal tumors (15 pancreatic, 7 hepatic and 3 LNs), the masses size measures about 4 cm, which are applicable for percutaneous needle insertion and associated with oligo or no metastatic lesion however patients with cardiac arrhythmias or pacemaker, patients unfit for general anesthesia, multiple metastatic lesions, patients with renal impairment and patient with metallic stent were excluded. Full radiological follow up was done as well. Results: There was significant reduction in level of tumor markers in pancreatic tumors after IRE in comparison to baseline level o as well as tumor size during different periods of follow up. The same was detected for hepatic focal lesions regard its size however metastasis was reported. While variable response was detected in LN ablation. Conclusion: The Irreversible electroporation is a promising less invasive technique for ablation of local solid tumors especially in pancreatic tumors. | ||
| Keywords | ||
| Irreversible electroporation (IRE); ablation; pancreatic tumors; hepatic focal lesions; metastatic LN; NHL | ||
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