Executive Function Impairment in Correlation with EEG Finding in Children with Type 1 DM at School Age | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 116, Volume 94, Issue 1, January 2024, Pages 793-798 PDF (615.37 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2024.343133 | ||
| Abstract | ||
| Background:The age of onset is an important characteristic of type 1 diabetes mellitus, influencing cognitive functions. Typically, earlier onset is associated with poorer cognitive performance. Objective: This study aimed to investigate the relationship between type 1 diabetes mellitus and cognitive dysfunction. Methods:This study included 100 children with type 1 diabetes mellitus (DM) and 20 apparently healthy children. They were divided as follows: The patient group (Group I) comprised 100 children with type 1 DM and the control group (Group II) consisted of twenty apparently healthy children. All participants underwent a comprehensive assessment including history-taking, sociodemographic data collection, general and local examination, and laboratory investigations. Results: A statistically significant association was found between "start the task" function and gender, with significantly higher mean scores observed in females (p = 0.003). Participants' weight and height showed statistically significant negative correlations with the "organized" function (p = 0.043 and 0.009, respectively). Moreover, the scores of "Block response" and "Working memory" were found to exhibit statistically significant positive correlations with TLC, RBCs, and Hb levels, while they showed significant negative correlations with HbA1c levels (p < 0.05). Conclusions: Children with type 1 diabetes mellitus demonstrated notable impairments in various executive functions, indicating a potential association between glycemic control, EEG findings, and cognitive dysfunction. Monitoring cognitive function alongside medical parameters could be crucial in managing type 1 diabetes mellitus in children. | ||
| Keywords | ||
| Executive function impairment; EEG finding; Children; Type 1 DM; School age | ||
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