Shabana, M., Hamdy, S., Samir, H., Zaki, N., Medhat, M. (2024). Ocular Torsions and the Subjective Visual Vertical with Brainstem and Cerebellar Lesions in Multiple Sclerosis.. test, 25(25), 1-10. doi: 10.21608/ejentas.2021.74485.1360
Mohamed Ibrahim Shabana; Sherif Hamdy; Hatem Samir; Noha Mohamed Magdi Zaki; Mariam Magdy Medhat. "Ocular Torsions and the Subjective Visual Vertical with Brainstem and Cerebellar Lesions in Multiple Sclerosis.". test, 25, 25, 2024, 1-10. doi: 10.21608/ejentas.2021.74485.1360
Shabana, M., Hamdy, S., Samir, H., Zaki, N., Medhat, M. (2024). 'Ocular Torsions and the Subjective Visual Vertical with Brainstem and Cerebellar Lesions in Multiple Sclerosis.', test, 25(25), pp. 1-10. doi: 10.21608/ejentas.2021.74485.1360
Shabana, M., Hamdy, S., Samir, H., Zaki, N., Medhat, M. Ocular Torsions and the Subjective Visual Vertical with Brainstem and Cerebellar Lesions in Multiple Sclerosis.. test, 2024; 25(25): 1-10. doi: 10.21608/ejentas.2021.74485.1360

Ocular Torsions and the Subjective Visual Vertical with Brainstem and Cerebellar Lesions in Multiple Sclerosis.

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Article 45, Volume 25, Issue 25, March 2024, Pages 1-10    PDF (410.44 K)
Document Type: Original Article
DOI: 10.21608/ejentas.2021.74485.1360
Authors
Mohamed Ibrahim Shabana1; Sherif Hamdy2; Hatem Samir3; Noha Mohamed Magdi Zaki* 4; Mariam Magdy Medhat5
1Department of Otorhinolaryngology (Audio-vestibular medicine), Faculty of Medicine, Cairo University, Cairo, Egypt
2Department of Neurology Faculty of Medicine, Cairo University, Cairo, Egypt
3Department of Neurology Faculty of Medicine- Cairo University, Cairo, Egypt
4Audivestibular medicine unit, ENT department, Benha University
5Department of Otorhinolaryngology (Audio-vestibular medicine) Faculty of Medicine-Cairo University, Cairo, Egypt
Abstract
Background: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system that makes a burden on patients and their families leading to disability especially in young patients. Acute or chronic lesions of MS within the brainstem and cerebellum frequently results in ocular motor disorders and deviation of subjective visual vertical (SVV).
Aim: Finding a feasible, convenient way to evaluate ocular motor disorders in MS patients with brainstem and cerebellar affection and also to investigate to what extent they have problems with the estimation of verticality and also to demonstrate the relationship with stages of MS and expanded disability status scale (EDSS).
Patients and Methods: Here, an observational case control study involving 95 patients: 65 patients with relapsing remitting multiple sclerosis all with brainstem and/or cerebellar affection and 30 healthy age and gender matched individual. MS patients were subjected to complete bedside evaluation, oculomotor testing and SVV testing while control group were subjected to subjective visual vertical evaluation.
Results: The study found that MS patients with brainstem and/or cerebellar affection experienced variety of ocular motor disorders. SVV abnormalities were detected with both cerebellar and brainstem lesions. SVV showed a highly statistically significant difference in both groups.
Conclusion: Clinical examination of eye movement and also SVV evaluation, takes only a few minutes to perform, but provide better information concerning the presence of brainstem and cerebellar involvement in MS patients.

Keywords
Brainstem; cerebellum; multiple sclerosis; oculomotor disorders; subjective visual vertical
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