Prevalence of Thyroid Dysfunction in Systemic Lupus Erythematosus of Bahraini Patients | ||
| Bulletin of Egyptian Society for Physiological Sciences | ||
| Article 10, Volume 33, Issue 1, June 2013, Pages 123-130 PDF (157.12 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/besps.2013.35194 | ||
| Authors | ||
| Ola ElSegai* 1; Eman Farid1; Reda Ebrahim2 | ||
| 1Department of Medical Biochemistry , Salmanya Medical Complex, Ministry of Health, Kingdom of Bahrain | ||
| 2Department of Internal Medicine, Salmanya Medical Complex, Ministry of Health, Kingdom of Bahrain | ||
| Abstract | ||
| Background: Controversy about the prevalence of thyroid dysfunction in systemic lupus erythematosus (SLE) patients has been reported. As no previous study evaluated thyroid status in SLE Bahraini (BSLE) patients, so, the current study aimed to evaluate the prevalence of thyroid dysfunction among those patients compared to an age and sex matched healthy control group. Methods: Retrospective laboratory data of the thyroid function in forty-three SLE Bahraini patients who were recently diagnosed and fulfilling four criteria of the American College of Rheumatology (ACR) criteria were evaluated. One hundred-fifty matched healthy controls were selected from the general population laboratory records for thyroid function screening or routine annual checkup. Results: The overall thyroid dysfunction among BSLE patients was 32.5% VS 12.6% in the control group (P<0.002). The most prevalent thyroid dysfunction in SLE patient was the subclinical form compared to the control group, the prevalence of subclinical hypothyroidism was significantly higher (P<0.002) whereas, subclinical hyperthyroidism was insignificantly different. Laboratory data did not reveal any overt thyroid dysfunction among patients and controls. Conclusion: Subclinical hypothyroidism was significantly higher among BSLE patients than in healthy controls. Physician during follow up of SLE patients should be alert for the development of overt thyroid dysfunction in high risk group especially the female gender. | ||
| Keywords | ||
| subclinical hypothyroidism; subclinical hyperthyroidism; Thyroid dysfunction; Systemic lupus erythematosus; Bahraini | ||
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