Molecular Characterization of Hydropericardium Hepatitis Syndrome in Broiler Chickens | ||
| Journal of Current Veterinary Research | ||
| Volume 6, Issue 1, April 2024, Pages 151-160 PDF (756.3 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jcvr.2024.352710 | ||
| Authors | ||
| Mohamed Hossiny* ; Alaa abdelrazek; Hesham Sultan | ||
| Abstract | ||
| Infection with fowl adenoviruses (FAdVs) can lead to a number of syndromes in chickens. These syndromes, which include inclusion body hepatitis (IBH) and hepatitishydropericardium syndrome (HHS), as well as others, are responsible for tremendous economic losses all over the world. FAdVs can be broken down into a total of 12 different serotypes and 5 different species (A–E; 1–8a and 8b–11). As a result of the extensive distribution of FAdV strains, the vast majority of bird species are susceptible to infection. IBH and HHS are both caused by viruses belonging to the genus aviadenovirus, which is a family within the adenoviridae viral family. In our study samples from IBH and HHS suspected outbreaks were collected from Alexandria, Mars Matroh and Behera governorates. The affected broilers showed enlarged liver and kidney, straw-colored fluid accumulates in the pericardial sac around the heart. The FAdVs infection confirmed by conventional PCR infection using Hexon gene specific primers then sequencing of 3 selected FAdv the isolates. Phylogentic analysis of the obtained sequences in comparing with reference strains from gene bank; the three isolates were highly similar to the circulating FAdV type D in Egypt with nucleotide identity ranged 99 -100% and amino acid identity ranged 97.2-100%. While they are of low similarity with the other FAdV serotypes located in group D FAdV. Interestingly we found that FAdV species D was predominant in Egypt now specially FAdVs- 2/11. | ||
| Keywords | ||
| FAdV; Hexon; HHS and IBH | ||
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