Comparative Study on the Efficacy of Antimicrobial Photodynamic Therapy Versus Antibiotic Therapy as an Adjunct to Non-Surgical Treatment in Managing Periodontitis (Stage II, Grade B) | ||
| Al-Azhar Assiut Dental Journal | ||
| Volume 7, Issue 1, April 2024, Pages 19-27 PDF (2.41 M) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aadj.2024.355431 | ||
| Author | ||
| ahmed mohamed EL SHARAKI* | ||
| Periodontology Department, Faculty of Oral and Dental Medicine, Zagazig University, Egypt. | ||
| Abstract | ||
| Aims: This study evaluates the comparative effectiveness of antimicrobial photodynamic therapy (aPDT) versus traditional antibiotic therapy when used in conjunction with SRP in the treatment of Periodontitis Grade B, Stage II.. Subjects and Methods: Sixty participants with Stage II, Grade B periodontitis were recruited from Zagazig University’s Faculty of Dentistry. Patients aged 20-40 received either antimicrobial photodynamic therapy (aPDT) or antibiotics alongside scaling and root planing (SRP). Clinical parameters including probing depth, clinical attachment level, and bleeding on probing were documented at baseline, 3 months, and 6 months post-intervention. Microbial analysis determined periodontopathogenic bacteria levels pre- and post-treatment. Treatment outcomes were analyzed using appropriate statistical methods. Results: Both therapies showed significant improvements in PD, CAL, and BOP from baseline to the 6-month follow-up. However, the aPDT group demonstrated statistically significant better outcomes in PD reduction and CAL gain at 3 and 6 months compared to the antibiotic group. Conclusion: The findings suggest that aPDT may be a more effective adjunct to SRP than antibiotics for the management of periodontitis (Stage II, Grade B). aPDT showed superior clinical and microbiological outcomes, indicating its potential as a non-antibiotic alternative in periodontal therapy. Further long-term studies are warranted to confirm these findings and to evaluate the sustainability of aPDT benefits | ||
| Keywords | ||
| Periodontitis; Antimicrobial Photodynamic Therapy; Antibiotic Therapy; NonSurgical Periodontal Treatment | ||
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