Khalil, H., El-Yazbi, A., Elkimary, E., Belal, T. (2024). Doping in sports: A survey of the analytical techniques unmasking the abuse of performance enhancing drugs.. test, 1(2), 60-85. doi: 10.21608/japs.2024.286122.1023
Hadeel Adel Khalil; Amira Fawzy El-Yazbi; Eman Ibrahim Elkimary; Tarek Saeid Belal. "Doping in sports: A survey of the analytical techniques unmasking the abuse of performance enhancing drugs.". test, 1, 2, 2024, 60-85. doi: 10.21608/japs.2024.286122.1023
Khalil, H., El-Yazbi, A., Elkimary, E., Belal, T. (2024). 'Doping in sports: A survey of the analytical techniques unmasking the abuse of performance enhancing drugs.', test, 1(2), pp. 60-85. doi: 10.21608/japs.2024.286122.1023
Khalil, H., El-Yazbi, A., Elkimary, E., Belal, T. Doping in sports: A survey of the analytical techniques unmasking the abuse of performance enhancing drugs.. test, 2024; 1(2): 60-85. doi: 10.21608/japs.2024.286122.1023

Doping in sports: A survey of the analytical techniques unmasking the abuse of performance enhancing drugs.

Journal of Advanced Pharmaceutical Sciences
Volume 1, Issue 2, June 2024, Pages 60-85    PDF (787.42 K)
Document Type: Review Article
DOI: 10.21608/japs.2024.286122.1023
Authors
Hadeel Adel Khalil* ; Amira Fawzy El-Yazbi; Eman Ibrahim Elkimary; Tarek Saeid Belal
Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Alexandria University.
Abstract
The use of illegal performance-enhancing drugs (PEDs) in sports, and other tactics by athletes to gain an unfair competitive advantage is becoming a global concern since it negatively impacts the athlete, participants, and the integrity of sports. Annually, a list of drugs and techniques that are prohibited from being used in sports is published by the World Anti-Doping Agency (WADA). The WADA list consists of different classes, namely, non-approved substances, anabolic androgenic steroids (AAS), peptide hormones, growth factors, related substances and mimetics, beta-2 agonists, hormone and metabolic modulators, diuretics and masking agents, stimulants, narcotics, cannabinoids, glucocorticoids, and beta blockers. Moreover, athletes tend to use other cheating techniques, such as blood doping, urine adulteration, and gene doping, to increase their chances of winning. This review encompasses the various classes of PEDs and methods that are most widely used to enhance the performance of athletes. In addition, herein we discuss some of the most commonly used methods that are implemented in the detection of doping.

Highlights
  • The use of illegal performance-enhancing drugs (PEDs), and other tactics by athletes to gain an unfair competitive advantage is becoming a global concern.
  • A list of drugs and techniques that are prohibited from being used in sports is annually published by the World Anti-Doping Agency (WADA).
  • This work reviews the different classes of PEDs and methods and summarizes the analytical techniques that are implemented in the detection of doping.
Keywords
Liquid chromatography; Mass spectrometry; Doping; Performance enhancing drugs (PEDs); World Anti-Doping Agency
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