Estimation of biofilm forming and antibiotic resistance of clinical Stenotrophomonas maltophilia in Ninawa hospitals, Iraq | ||
| Microbes and Infectious Diseases | ||
| Articles in Press, Accepted Manuscript, Available Online from 10 June 2024 PDF (580.69 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mid.2024.290388.1952 | ||
| Authors | ||
| Suhail Jawdat Fadhil1; Sawsan M. Alomari2; Alaa Nazar Al-Najim2; Razan Y. Qasinr3; ali m saadi* 1 | ||
| 1Department of Anesthesia Techniques, Mosul Medical Technical Institute, Northern Technical University, Iraq | ||
| 2Department of Medical Laboratory Technologies, Mosul Medical Technical Institute, Northern Technical University, Iraq | ||
| 3Department of Pharmacy Technologies, Mosul Medical Technical Institute, Northern Technical University, Iraq | ||
| Abstract | ||
| Background: Stenotrophomonas maltophilia is an emerging multiresistant nosocomial pathogen. Aim: This study aimed to isolate S. maltophilia and estimate the frequency of biofilm forming as a virulence factor contributing with resistance to some antibiotics. Methods: A total of 350 samples were collected from (100) patients in different hospitals of Mosul city during the period from April 2022 to June 2023. Using conventional methods and Vitek 2 automated system. Results: The highest isolation rate of S. maltophilia was from blood samples at rate of 51.5%, urine and wound 28.5% , 20% respectively while there was no isolates in pharynx samples, the disc diffusion method used to confirm the resistant of bacterial strains against 10 antimicrobial agents, most of them showed high resistant rates to Amikacin (57.1%), Ceftazidime (62.8%), Ciprofloxacin (85.7%), Piperacillin (77.1%), Cefepime and Gentamicin (71.4%), while it was low against Imipenem (42.8), Meropenem (45.7%) and Cefotaxime (45.71%) also for Piperacillin-tazobactam (48.5%), The resistance level was > 60 % for the most tested antimicrobial agents. The biofilm formation was implemented using microtiter plate method, about (31.43%) of the isolates induced strong level of biofilm formation, (42.85%) moderate while only (25.72%) showed weak intensity of biofilm formation, Conclusion: The high resistance of Stenotrophomonas maltophilia to most of the antibiotics used is an indicator that requires attention, in addition most of the resistant isolates had strong biofilm production properties which refer to the virulently of this bacteria relating with serious nosocomial infections. | ||
| Keywords | ||
| Keywords : Stenotrophomonas maltophilia; antibiotic sensitivity test; virulence factors; Biofilm forming | ||
|
Statistics Article View: 204 PDF Download: 134 |
||
