Predictors of recurrence of arterial lesions after surgical repair in Behçet’s disease | ||
| The Egyptian Journal of Surgery | ||
| Volume 41, Issue 4, October 2022 PDF (777.46 K) | ||
| DOI: 10.4103/ejs.ejs_253_22 | ||
| Authors | ||
| Mohamed Sabry; Sayed Younis; Hany A. Mohamed | ||
| Abstract | ||
| Background Behçet’s disease (BD) is an aggressively devastating systemic vasculitis that involves multiple systems and is characterized by unexpected periods of exacerbations and remissions. When vascular complications dominate the clinical presentation, the term vasculo-BD is used. This study aimed to present our experience in the surgical management of vasculo-BD arterial lesions, the recurrence rate, and the factors associated with this recurrence. Patients and method s This is a retrospective study that included an analysis of a prospectively maintained database of patients with vasculo-BD who underwent surgical repair for arterial lesions. Patients’ data and outcome after 2-year follow-up were recorded. Results This study included 16 patients with vasculo-BD. Three (18.75%) patients indicated surgery owing to arterial thrombosis, and 13 (81.25%) patients had arterial aneurysms. The aorta was affected in five (31.25%) patients and the peripheral arteries in 11 (68.75%) patients. Immediate technical success was obtained in all cases (100%). Minor complications were shown in four (25%) patients. A total of 10 (62.5%) patients had postoperative recurrence. The recurrence occurrence decreased significantly with the use of sleeve protection (=0.039) and immunosuppressive drugs (=0.039). The recurrence-free survival was significantly longer in patients who underwent sleeve protection and received immunosuppressive therapy. Conclusion The surgical approach for arterial lesions in patients with BD is associated with a high recurrence rate. Sleeve protection and considering the immunosuppressive therapy influenced the recurrence rate and recurrence-free survival. | ||
| Keywords | ||
| arterial lesions; Behçet’s disease; Recurrence; surgical management; vasculo-Behçet’s disease | ||
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