Use of Lyophilized Growth Factors Foam in Chronic Ulcers

Kahle B., Hermanns H.J. and Gallenkemper G.: Evidence-
based treatment of chronic leg ulcers. Dtsch Arztebl
Int., Apr. 108 (14): 231-7, 2011. doi: 10.3238/arztebl.
2011.0231.
2- Qu S., Hu Z., Zhang Y., Wang P., Li S., Huang S., Dong
Y., Xu H., Rong Y, Zhu W., Tang B. and Zhu J.: Clinical
Studies on Platelet-Rich Plasma Therapy for Chronic
Cutaneous Ulcers: A Systematic Review and Meta-Analysis
of Randomized Controlled Trials. Adv Wound Care
(New Rochelle), Feb. 11 (2): 56-69, 2022. doi: 10.1089/
wound.2020.1186.
3- HUBER S.C., DE MORAES MARTINELLI B., QUINTERO
M., DE PAULA L.Í.S., CATALDO J.L., DE LIMA
MONTALVÃO S.A. and ANNICHINO-BIZZACCHI
J.M.: A case series of platelet rich plasma in chronic venous
ulcers. Regen Ther., Apr. 5; 18: 51-58, 2021. doi:
10.1016/j.reth.2021.03.005.
4- Hesseler M.J. and Shyam N.: Platelet-rich plasma and its
utility in medical dermatology: A systematic review. J.
Am. Acad. Dermatol., Sep. 81 (3): 834-846, 2019. doi:
10.1016/j.jaad.2019.04.037.
5- QU W., WANG Z., HUNT C., MORROW A.S., URTECHO
M., AMIN M., SHAH S., HASAN B., ABD-RABU
R., ASHMORE Z., KUBROVA E., PROKOP L.J. and
MURAD M.H.: The Effectiveness and Safety of Platelet-
Rich Plasma for Chronic Wounds: A Systematic Review
and Meta-analysis. Mayo. Clin. Proc., Sep. 96 (9): 2407-
2417, 2021. doi: 10.1016/j.mayocp.2021.01.030.
6- PINTO J.M., PIZANI N.S., KANG H.C. and SILVA L.A.:
Application of platelet-rich plasma in the treatment of
chronic skin ulcer - case report. An Bras Dermatol.,
Jul-Aug. 89 (4): 638-40, 2014. doi: 10.1590/abd1806-
4841.20143004.
7- Greenhalgh D.G.: The role of growth factors in wound healing.
J. Trauma., Jul. 41 (1): 159-67, 1996. doi: 10.1097/
00005373-199607000-00029.
8- UYSAL A.C., MIZUNO H., TOBITA M., et al.: The effect
of adipose-derived stem cells on ischemia-reperfusion injury:
immunohistochemical and ultrastructural evaluation.
Plast Reconstr. Surg., 124: 804-815, 2009.
9- Mardani M., Asadi-Samani M., Rezapour S., et al.: Evaluation
of bred fish and seawater fish in terms of nutritional
value, and heavy metals. J. Chem. Pharm. Sci., 9: 1277-
1283, 2016.
10- MARDANI M., MAHMOUD B., MORADMAND J.S., et
al.: Comparison of the descurainia sophia and levostatin
Egypt, J. Plast. Reconstr. Surg., July 2024 215
effect on the ldl cholesterol reduction, a clinical trial study.
J. Chem. Pharm. Sci., 9: 1329-1333, 2016.
11- Ghafarzadeh M. and Eatemadi A.: Clinical efficacy of liposome-
encapsulated Aloe vera on melasma treatment during
pregnancy. J. Cosmet Laser Ther., 19: 181-187, 2017.
12- Nie C., Yang D., Xu J., et al.: Locally administered Adipose-
derived stem cells accelerate wound healing through
differentiation and vasculogenesis. Cell Transplant, 20:
205-216, 2011.
13- Jaferian S., Soleymaninejad M., Negahdari B., et al.: Stem
cell, biomaterials and growth factors therapy for hepatocellular
carcinoma. Biomed Pharmacother., 88: 1046-
1053, 2017.
14- Lee S.H., Lee J.H. and Cho K.H.: Effects of human adipose-
derived stem cells on cutaneous wound healing in
nude mice. Ann. Dermatol., 23: 150-155, 2011.
15- Jaferian S., Soleymaninejad M. and Daraee H.: Verapamil
(VER) enhances the cytotoxic effects of docetaxel and
vinblastine combined therapy against non-small cell lung
cancer cell lines. Drug Res. (Stuttg), 68, 2017. DOI:https://
doi.org/10.1055/s-0043-117895
16- Huang S-P., Hsu C-C. and Chang S-C., et al.: Adiposederived
stem cells seeded on acellular dermal matrix grafts
enhance wound healing in a murine model of a full-thickness
defect. Ann. Plast. Surg., 69: 656-662, 2012.
17- Suthar M., Gupta S., Bukhari S. and Ponemone V.: Treatment
of chronic non-healing ulcers using autologous
platelet rich plasma: A case series. J. Biomed Sci., Feb.
27; 24 (1): 16, 2017. doi: 10.1186/s12929-017-0324-1.
18- Park J.W., Hwang SR. and Yoon I.S.: Advanced Growth
Factor Delivery Systems in Wound Management and Skin
Regeneration. Molecules, Jul. 27; 22 (8): 1259, 2017. doi:
10.3390/molecules22081259.
19- Hassan M.H., Abd El-Rahman S.S., Amer M.S., Fahmy
H.M. and Shamaa A.A.: Effect of lyophilized growth factors
(LGF) derived from equine platelets on experimentally
induced skin wound healing in mongrel dogs. International
Journal of Veterinary Science, 10 (2): 75-82, 2021.
https://doi.org/10.47278/journal.ijvs/2020.012.
20- Dogra S. and Sarangal R.: Summary of recommendations
for leg ulcers. Indian Dermatol Online J., Jul. 5 (3): 400-7,
2014. doi: 10.4103/2229-5178.137829.
21- Shi C., Dumville J.C., Cullum N., Connaughton E. and
Norman G.: Compression bandages or stockings versus
no compression for treating venous leg ulcers. Cochrane
Database Syst. Rev., Jul. 26; 7 (7): CD013397, 2021. doi:
10.1002/14651858.CD013397.pub2.
22- Gethin G., Cowman S. and Kolbach D.N.: Debridement
for venous leg ulcers. Cochrane Database Syst Rev., Sep.
14; 2015 (9): CD008599, 2015. doi: 10.1002/14651858.
CD008599.pub2.
23- Jull A., Waters J. and Arroll B.: Pentoxifylline for treatment
of venous leg ulcers: Aa systematic review. Lancet,
May 4; 359 (9317): 1550-4, 2002. doi: 10.1016/S0140-
6736(02)08513-6.
24- Layton A.M., Ibbotson S.H., Davies J.A. and Goodfield
M.J.: Randomised trial of oral aspirin for chronic venous
leg ulcers. Lancet, Jul. 16; 344 (8916): 164-5, 1994.
25- Ubbink D.T., Westerbos S.J., Evans D., Land L. and Vermeulen
H.: Topical negative pressure for treating chronic
wounds. Cochrane Database Syst. Rev., Jul. 16; (3):
CD001898, 2008. doi: 10.1002/14651858.CD001898.
pub2.
26- Jones J.E., Nelson E.A. and Al-Hity A.: Skin grafting for
venous leg ulcers. Cochrane Database Syst. Rev., Jan.
31; 2013 (1): CD001737, 2013. doi: 10.1002/14651858.
CD001737.pub4.
27- Schreml S., Szeimies R.M., Prantl L., Landthaler M. and
Babilas P.: Wound healing in the 21st century. J. Am. Acad.
Dermatol., Nov. 63 (5): 866-81, 2010. doi: 10.1016/j.
jaad.2009.10.048.
28- Robson M.C., Steed D.L. and Franz M.G.: Wound healing:
Biologic features and approaches to maximize healing
trajectories. Curr. Probl. Surg., Feb. 38 (2): 72-140, 2001.
doi: 10.1067/msg.2001.111167.
29- Barrientos S., Brem ., Stojadinovic O. and Tomic-Canic
M.: Clinical application of growth factors and cytokines in
wound healing. Wound Repair Regen., Sep-Oct. ;22 (5):
569-78, 2014. doi: 10.1111/wrr.12205.
30- Ito K., Ito S., Sekine M. and Abe M.: Reconstruction of
the soft tissue of a deep diabetic foot wound with artificial
dermis and recombinant basic fibroblast growth factor.
Plast. Reconstr. Surg., Feb. 115 (2): 567-72, 2005. doi:
10.1097/01.prs.0000149485.60638.30.
31- Tiaka E.K., Papanas N., Manolakis A.C. and Georgiadis
G.S.: Epidermal growth factor in the treatment
of diabetic foot ulcers: An update. Perspect Vasc.
Surg. Endovasc. Ther., Mar. 24 (1): 37-44, 2012. doi:
10.1177/1531003512442093.
32- Fernández-Montequín J.I., Betancourt B.Y., Leyva-Gonzalez
G., Mola E.L., Galán-Naranjo K., Ramírez-Navas
M., Bermúdez-Rojas S., Rosales F., García-Iglesias E.,
Berlanga-Acosta J., Silva-Rodriguez R., Garcia-Siverio
M. and Martinez L.H.: Intralesional administration of
epidermal growth factor-based formulation (Heberprot-P)
in chronic diabetic foot ulcer: Treatment up to complete
wound closure. Int. Wound J., Feb. 6 (1): 67-72, 2009. doi:
10.1111/j.1742-481X.2008.00561.x.
33- Da Silva L.Q., Montalvão S.A.L., Justo-Junior A.D.S.,
Cunha Júnior J.L.R., Huber S.C., Oliveira C.C. and Annichino-
Bizzacchi J.M.: Platelet-rich plasma lyophilization
enables growth factor preservation and functionality
when compared with fresh platelet-rich plasma. Regen
Med., Oct. 13 (7): 775-784, 2018. doi: 10.2217/rme-2018-
0035.
34- Hariprasad R., Suganya T.L., John S.S., Raj P.R., Kuriakose
F. and Anoop V.N.: Assessment of Growth Factors
with Three Different Platelet Preparations, Namely
Platelet-Rich Fibrin, Platelet-Rich Plasma, and Lyophilized
Platelet: An In vitro Study. J. Pharm Bioallied Sci.,
Nov. 13 (Suppl 2): S1696-S1699, 2021. doi: 10.4103/jpbs.
jpbs_358_21.