Shahin, R., Yousef, Y., Ibrahim, M. (2019). Protective Efficacy of Some Newcastle Disease Virus (NDV) Vaccination Programs Against Velogenic NDV Genotype VII in Broiler Chickens. test, 1(1), 103-114. doi: 10.21608/jcvr.2019.36559
Rahma Shahin; Yousef Yousef; Mahmoud Ibrahim. "Protective Efficacy of Some Newcastle Disease Virus (NDV) Vaccination Programs Against Velogenic NDV Genotype VII in Broiler Chickens". test, 1, 1, 2019, 103-114. doi: 10.21608/jcvr.2019.36559
Shahin, R., Yousef, Y., Ibrahim, M. (2019). 'Protective Efficacy of Some Newcastle Disease Virus (NDV) Vaccination Programs Against Velogenic NDV Genotype VII in Broiler Chickens', test, 1(1), pp. 103-114. doi: 10.21608/jcvr.2019.36559
Shahin, R., Yousef, Y., Ibrahim, M. Protective Efficacy of Some Newcastle Disease Virus (NDV) Vaccination Programs Against Velogenic NDV Genotype VII in Broiler Chickens. test, 2019; 1(1): 103-114. doi: 10.21608/jcvr.2019.36559

Protective Efficacy of Some Newcastle Disease Virus (NDV) Vaccination Programs Against Velogenic NDV Genotype VII in Broiler Chickens

Journal of Current Veterinary Research
Article 11, Volume 1, Issue 1, June 2019, Pages 103-114    PDF (1.1 M)
Document Type: Original Article
DOI: 10.21608/jcvr.2019.36559
Authors
Rahma Shahin1; Yousef Yousef2; Mahmoud Ibrahim* 3
1Birds and Rabbit Medicin Department, Fac. of Vet. Medicin, Sadat City University, Menofia, Egypt
2Poultry Disease Department, Fac. of Vet. Medicin, Cairo University, Cairo, Egypt
3Birds and Rabbits Medicine department, Faculty of Veterinary Medicine, Sadat City University, Menoufia, Egypt
Abstract
The protective efficacy of live and inactivated NDV- genotype II vaccines against challenge with velogenic Newcastle disease virus (VNDV) genotype VII (Chicken/USC/Egypt/2014), was evaluated in vaccinated groups (G1, G2, G3, G4 and G5) with inactivated vaccine on day 7 and live vaccine (LaSota) on days 7 and 15, in addition, with live V4 strain either on day 1 (G1) or on day 25 (G2) or in both days 1 and 25 (G3) and challenged on day 32 of age. The protection percentages were 96%, 96%, 96% and 88% in G1, G2, G3 & G4, respectively, vs 4% in non-vaccinated challenged chickens (G5). Moreover, the tracheal and cloacal viral shedding were 30% & 100% ; 0% & 0% ; 0% & 30%; 0% & 30% in vaccinated challenged G1, G2, G3 & G4, respectively, vs 100% & 60% in non-vaccinated challenged G5 at 3 DPC, whereas, the tracheal and cloacal viral shedding were 0% & 30% ; 0% & 0% ; 0% & 0% ; 30% & 60% in vaccinated challenged G1, G2, G3 & G4, respectively, vs 100% & 100% non-vaccinated challenged G5 at 7 dpc. However, the clinical signs, gross lesions and serological response were monitored till 14 dpc. Our results revealed that the inclusion of  V4 vaccine  strain in vaccination program is providing  superior protection against NDV genotype VII and good safely replace live (LaSota) in early and late vaccination practices.
Keywords
Vaccination; Newcastle disease; genotype VII; V4 strain
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