B, K., Moustafa, H. (1937). TOXIC EFFECTS OF PIRPROFEN ON CHROMOSOMES AND BLOOD CRITERIA IN MICE. test, 37(1), 33-45. doi: 10.21608/vmjg.1937.368272
Kamilia B; H Moustafa. "TOXIC EFFECTS OF PIRPROFEN ON CHROMOSOMES AND BLOOD CRITERIA IN MICE". test, 37, 1, 1937, 33-45. doi: 10.21608/vmjg.1937.368272
B, K., Moustafa, H. (1937). 'TOXIC EFFECTS OF PIRPROFEN ON CHROMOSOMES AND BLOOD CRITERIA IN MICE', test, 37(1), pp. 33-45. doi: 10.21608/vmjg.1937.368272
B, K., Moustafa, H. TOXIC EFFECTS OF PIRPROFEN ON CHROMOSOMES AND BLOOD CRITERIA IN MICE. test, 1937; 37(1): 33-45. doi: 10.21608/vmjg.1937.368272

TOXIC EFFECTS OF PIRPROFEN ON CHROMOSOMES AND BLOOD CRITERIA IN MICE

Veterinary Medical Journal (Giza)
Volume 37, Issue 1, January 1989, Pages 33-45    PDF (6.52 M)
Document Type: Original Article
DOI: 10.21608/vmjg.1937.368272
Authors
Kamilia B* ; H Moustafa
National research center, Dokki, Giza, Egypt
Abstract
Pirprofen (Rengasi1)® is one of the recent nonsteroidal anti-inflammatory antirheumatic drugs of propionic acid derivative. This study was carried out on female mice for 19 days using three different doses, to evaluate the cytogenetic and haematological effects of piroprofen on chromosomesand blood picture to get a conclusion about its side effects. At dose levelsof 90 & 112.5 mg.kg.b.wt pirprofen did not induce any significant increase in chromosom abberrations. However after treatment with 450 mg/Kg. was a significant increase in chromosomal aberrations found.
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